2. PI3K/Akt/mTOR
  3. PIN1
  4. BCPA

BCPA is a Pin1 regulator without cytotoxicity. BCPA attenuates the reduction of Pin1 protein to inhibit receptor activator of RANKL-induced osteoclastogenesis. BCPA regulates osteoclast activation, used to osteoporosis research.

For research use only. We do not sell to patients.

BCPA Chemical Structure

BCPA Chemical Structure

CAS No. : 547731-67-9

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Based on 1 publication(s) in Google Scholar

BCPA Related Antibodies

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Description

BCPA is a Pin1 regulator without cytotoxicity. BCPA attenuates the reduction of Pin1 protein to inhibit receptor activator of RANKL-induced osteoclastogenesis. BCPA regulates osteoclast activation, used to osteoporosis research[1].

Molecular Weight

417.33

Formula

C22H22Cl2N2O2
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(NCCCCNC(/C=C/C1=C(Cl)C=CC=C1)=O)/C=C/C2=C(Cl)C=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 6.67 mg/mL (15.98 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3962 mL 11.9809 mL 23.9619 mL
5 mM 0.4792 mL 2.3962 mL 4.7924 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3962 mL 11.9809 mL 23.9619 mL 59.9046 mL
5 mM 0.4792 mL 2.3962 mL 4.7924 mL 11.9809 mL
10 mM 0.2396 mL 1.1981 mL 2.3962 mL 5.9905 mL
15 mM 0.1597 mL 0.7987 mL 1.5975 mL 3.9936 mL
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BCPA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BCPA547731-67-9PIN1peptidylprolyl cis/trans isomerase, NIMA-interacting 1Inhibitorinhibitorinhibit

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