2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. BE-10988

BE-10988 is a DNA topoisomerase inhibitor. BE-10988 inhibits the growth of Doxorubicin (HY-15142A)-resistant and vincristine-resistant P388 mouse leukemia cell lines by increasing the formation of DNA topoisomerase complexes.

For research use only. We do not sell to patients.

BE-10988 Chemical Structure

BE-10988 Chemical Structure

CAS No. : 135261-89-1

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BE-10988 Related Antibodies

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Description

BE-10988 is a DNA topoisomerase inhibitor. BE-10988 inhibits the growth of Doxorubicin (HY-15142A)-resistant and vincristine-resistant P388 mouse leukemia cell lines by increasing the formation of DNA topoisomerase complexes[1].

Molecular Weight

302.31

Formula

C13H10N4O3S
CAS No.
SMILES

O=C(C1=CSC(C2=CN(C)C(C(C=C3N)=O)=C2C3=O)=N1)N
Structure Classification
Initial Source

Actinomycetes
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BE-10988 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BE-10988135261-89-1BE10988BE 10988TopoisomeraseinhibitorDrug resistanceP388 mouse leukemia cell lineInhibitorinhibit

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HY-167671
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