2. Membrane Transporter/Ion Channel Neuronal Signaling Anti-infection
  3. Calcium Channel Sodium Channel SARS-CoV
  4. Bepridil

Bepridil  (Synonyms: (±)-Bepridil; Org 5730)

Cat. No.: HY-16952
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Bepridil ((±)-Bepridil) is a calcium channel blocking agent used as antiarrhythmic agent. Bepridil inhibits both calcium and sodium currents, has research potential in certain ischemia-induced ventricular arrhythmias. Bepridil also has strong inhibition of SARS-CoV-2 from entry and replication inside Vero E6 and A549 cells.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Bepridil hydrochloride and Bepridil hydrochloride hydrate) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Bepridil Chemical Structure

Bepridil Chemical Structure

CAS No. : 64706-54-3

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Bepridil Related Antibodies

Top Publications Citing Use of Products

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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Description

Bepridil ((±)-Bepridil) is a calcium channel blocking agent used as antiarrhythmic agent. Bepridil inhibits both calcium and sodium currents, has research potential in certain ischemia-induced ventricular arrhythmias. Bepridil also has strong inhibition of SARS-CoV-2 from entry and replication inside Vero E6 and A549 cells[1][2].

IC50 & Target

Calcium channel, Sodium channel, SARS-CoV-2[1][2]
Molecular Weight

366.54

Formula

C24H34N2O
CAS No.
SMILES

CC(COCC(CN(C1=CC=CC=C1)CC2=CC=CC=C2)N3CCCC3)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Bepridil Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bepridil64706-54-3(±)-Bepridil Org 5730Org5730Org 5730Org-5730Calcium ChannelSodium ChannelSARS-CoVCa2+ channelsCa channelsNa channelsNa+ channelsSARS coronavirusAntivirusantiarrhythmicSARS-CoV-2Inhibitorinhibitorinhibit

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