2. Epigenetics
  3. Epigenetic Reader Domain
  4. BET-IN-8

BET-IN-8 (Compound 27) is a potent inhibitor of BET with a Ki and Kd of 0.83 and 0.571 μM, respectively. BET-IN-8 ameliorates LPS-induced sepsis in vivo. BET-IN-8 has the potential for the research of sepsis.

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BET-IN-8 Chemical Structure

BET-IN-8 Chemical Structure

CAS No. : 2769893-19-6

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BET-IN-8 Related Antibodies

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Description

BET-IN-8 (Compound 27) is a potent inhibitor of BET with a Ki and Kd of 0.83 and 0.571 μM, respectively. BET-IN-8 ameliorates LPS-induced sepsis in vivo. BET-IN-8 has the potential for the research of sepsis[1].

Molecular Weight

423.48

Formula

C22H21N3O4S
CAS No.
SMILES

COC1=CC(C2=C(C(NC(SCC3=CC=CC=C3C)=N2)=O)C#N)=CC(OC)=C1OC
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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BET-IN-8 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BET-IN-82769893-19-6Epigenetic Reader DomainBETLPS-inducedsepsisInhibitorinhibitorinhibit

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