2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. Bimatoprost-d5

Bimatoprost-d5  (Synonyms: AGN 192024 d5)

Cat. No.: HY-B0191S Purity: 98.24%
COA Handling Instructions

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Bimatoprost-d5 is a deuterium labeled Bimatoprost. Bimatoprost is a prostaglandin analog and is a topical hypotensive agent frequently used for treating ocular hypertension and glaucoma. Bimatoprost also has an antiadipogenic effect[1][2].

For research use only. We do not sell to patients.

Bimatoprost-d<sub>5</sub> Chemical Structure

Bimatoprost-d5 Chemical Structure

Size Price Stock Quantity
1 mg USD 750 In-stock
5 mg USD 2250 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Bimatoprost-d5:

Bimatoprost-d5 Related Antibodies

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Description

Bimatoprost-d5 is a deuterium labeled Bimatoprost. Bimatoprost is a prostaglandin analog and is a topical hypotensive agent frequently used for treating ocular hypertension and glaucoma. Bimatoprost also has an antiadipogenic effect[1][2].

Molecular Weight

420.60

Formula

C25H32D5NO4
Unlabeled CAS

155206-00-1
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC([2H])([2H])C([2H])([2H])[2H])CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C[C@@H]1O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (237.76 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 100 mg/mL (237.76 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3776 mL 11.8878 mL 23.7756 mL
5 mM 0.4755 mL 2.3776 mL 4.7551 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.3776 mL 11.8878 mL 23.7756 mL 59.4389 mL
5 mM 0.4755 mL 2.3776 mL 4.7551 mL 11.8878 mL
10 mM 0.2378 mL 1.1888 mL 2.3776 mL 5.9439 mL
15 mM 0.1585 mL 0.7925 mL 1.5850 mL 3.9626 mL
20 mM 0.1189 mL 0.5944 mL 1.1888 mL 2.9719 mL
25 mM 0.0951 mL 0.4755 mL 0.9510 mL 2.3776 mL
30 mM 0.0793 mL 0.3963 mL 0.7925 mL 1.9813 mL
40 mM 0.0594 mL 0.2972 mL 0.5944 mL 1.4860 mL
50 mM 0.0476 mL 0.2378 mL 0.4755 mL 1.1888 mL
60 mM 0.0396 mL 0.1981 mL 0.3963 mL 0.9906 mL
80 mM 0.0297 mL 0.1486 mL 0.2972 mL 0.7430 mL
100 mM 0.0238 mL 0.1189 mL 0.2378 mL 0.5944 mL
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Bimatoprost-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bimatoprost-d5AGN 192024 d5Prostaglandin ReceptorDeuteriumlabeledhypotensivecular hypertensionglaucomaantiadipogenicInhibitorinhibitorinhibit

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