2. Neuronal Signaling Membrane Transporter/Ion Channel
  3. Cholinesterase (ChE) GABA Receptor iGluR
  4. Bis(7)-tacrine dihydrochloride

Bis(7)-tacrine dihydrochloride is a dimeric AChE inhibitor derived from tacrine. Bis(7)-tacrine dihydrochloride prevents glutamate-induced neuronal apoptosis by blocking NMDA receptors. Bis(7)-tacrine dihydrochloride is a potent GABAAreceptor antagonist. Bis(7)-tacrine dihydrochloride has the potential for the research of Alzheimer's disease .

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Bis(7)-tacrine dihydrochloride Chemical Structure

Bis(7)-tacrine dihydrochloride Chemical Structure

CAS No. : 224445-12-9

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Based on 1 publication(s) in Google Scholar

Bis(7)-tacrine dihydrochloride Related Antibodies

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Description

Bis(7)-tacrine dihydrochloride is a dimeric AChE inhibitor derived from tacrine. Bis(7)-tacrine dihydrochloride prevents glutamate-induced neuronal apoptosis by blocking NMDA receptors. Bis(7)-tacrine dihydrochloride is a potent GABAAreceptor antagonist. Bis(7)-tacrine dihydrochloride has the potential for the research of Alzheimer's disease [1][2][3].

Molecular Weight

565.62

Formula

C33H42Cl2N4
CAS No.
SMILES

[H]N(C1=C2C(C=CC=C2)=NC3=C1CCCC3)CCCCCCCN(C4=C5C=CC=CC5=NC6=C4CCCC6)[H].Cl.Cl
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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Bis(7)-tacrine dihydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bis(7)-tacrine224445-12-9Cholinesterase (ChE)GABA ReceptoriGluRGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorIonotropic glutamate receptorsAlzheimer's diseaseNMDA receptorGABAA receptorInhibitorinhibitorinhibit

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