2. Apoptosis Autophagy
  3. Apoptosis Autophagy
  4. Bisdemethoxycurcumin-d8

Bisdemethoxycurcumin-d8  (Synonyms: Curcumin III-d8; Didemethoxycurcumin-d8)

Cat. No.: HY-N0007S Purity: ≥98.0%
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Bisdemethoxycurcumin-d8 is the deuterium labeled Bisdemethoxycurcumin. Bisdemethoxycurcumin(Curcumin III; Didemethoxycurcumin) is a natural derivative of curcumin with anti-inflammatory and anti-cancer activities.

For research use only. We do not sell to patients.

Bisdemethoxycurcumin-d<sub>8</sub> Chemical Structure

Bisdemethoxycurcumin-d8 Chemical Structure

CAS No. : 2470233-08-8

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1 mg USD 450 In-stock
5 mg USD 1280 In-stock
10 mg USD 2050 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Bisdemethoxycurcumin-d8:

Bisdemethoxycurcumin-d8 Related Antibodies

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  • Purity & Documentation

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Description

Bisdemethoxycurcumin-d8 is the deuterium labeled Bisdemethoxycurcumin. Bisdemethoxycurcumin(Curcumin III; Didemethoxycurcumin) is a natural derivative of curcumin with anti-inflammatory and anti-cancer activities.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bisdemethoxycurcumin-d8 Related Antibodies
Molecular Weight

316.38

Formula

C19H8D8O4
CAS No.
Unlabeled CAS

33171-05-0
Appearance

Solid

Color

Yellow to orange

SMILES

O=C(CC(/C=C/C1=C([2H])C([2H])=C(O)C([2H])=C1[2H])=O)/C=C/C2=C([2H])C([2H])=C(O)C([2H])=C2[2H]
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (316.08 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 100 mg/mL (316.08 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1608 mL 15.8038 mL 31.6076 mL
5 mM 0.6322 mL 3.1608 mL 6.3215 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 3.1608 mL 15.8038 mL 31.6076 mL 79.0189 mL
5 mM 0.6322 mL 3.1608 mL 6.3215 mL 15.8038 mL
10 mM 0.3161 mL 1.5804 mL 3.1608 mL 7.9019 mL
15 mM 0.2107 mL 1.0536 mL 2.1072 mL 5.2679 mL
20 mM 0.1580 mL 0.7902 mL 1.5804 mL 3.9509 mL
25 mM 0.1264 mL 0.6322 mL 1.2643 mL 3.1608 mL
30 mM 0.1054 mL 0.5268 mL 1.0536 mL 2.6340 mL
40 mM 0.0790 mL 0.3951 mL 0.7902 mL 1.9755 mL
50 mM 0.0632 mL 0.3161 mL 0.6322 mL 1.5804 mL
60 mM 0.0527 mL 0.2634 mL 0.5268 mL 1.3170 mL
80 mM 0.0395 mL 0.1975 mL 0.3951 mL 0.9877 mL
100 mM 0.0316 mL 0.1580 mL 0.3161 mL 0.7902 mL
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Bisdemethoxycurcumin-d8 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bisdemethoxycurcumin-d82470233-08-8Curcumin III-d8Didemethoxycurcumin-d8ApoptosisAutophagyInhibitorinhibitorinhibit

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