2. Metabolic Enzyme/Protease
  3. DGK
  4. BMS-496

BMS-496 is adualDGKα/ζlipid kinase inhibitor, with theIC50of 0.09 (DGKα) and 0.006 μM (DGKζ).

For research use only. We do not sell to patients.

BMS-496 Chemical Structure

BMS-496 Chemical Structure

CAS No. : 2407854-31-1

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Based on 1 publication(s) in Google Scholar

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Description

BMS-496 is adualDGKα/ζlipid kinase inhibitor, with theIC50of 0.09 (DGKα) and 0.006 μM (DGKζ)[1].

IC50 & Target

0.09, 0.006 μM (DGKα,DGKζ)[1].
Molecular Weight

570.39

Formula

C26H22BrF2N5O3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CN(C1=CC=C(Br)N=C1C(N2CCN(C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC2)=C5[N+]([O-])=O)C5=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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BMS-496 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMS-4962407854-31-1BMS496BMS 496DGKDiacylglycerol kinase| T cellimmune checkpointPD-1syngeneic mouse tumor modelInhibitorinhibitorinhibit

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