2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. Boc-Gln-Ala-Arg-AMC acetate

Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Boc-Gln-Ala-Arg-AMC acetate Chemical Structure

Boc-Gln-Ala-Arg-AMC acetate Chemical Structure

Size Price Stock Quantity
1 mg USD 60 In-stock
5 mg USD 170 In-stock
10 mg USD 270 In-stock
25 mg USD 540 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Boc-Gln-Ala-Arg-AMC acetate:

Boc-Gln-Ala-Arg-AMC acetate Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2[1][2].

IC50 & Target

Trypsin[1]
Molecular Weight

690.74

Formula

C31H46N8O10
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (180.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4477 mL 7.2386 mL 14.4772 mL
5 mM 0.2895 mL 1.4477 mL 2.8954 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4477 mL 7.2386 mL 14.4772 mL 36.1931 mL
5 mM 0.2895 mL 1.4477 mL 2.8954 mL 7.2386 mL
10 mM 0.1448 mL 0.7239 mL 1.4477 mL 3.6193 mL
15 mM 0.0965 mL 0.4826 mL 0.9651 mL 2.4129 mL
20 mM 0.0724 mL 0.3619 mL 0.7239 mL 1.8097 mL
25 mM 0.0579 mL 0.2895 mL 0.5791 mL 1.4477 mL
30 mM 0.0483 mL 0.2413 mL 0.4826 mL 1.2064 mL
40 mM 0.0362 mL 0.1810 mL 0.3619 mL 0.9048 mL
50 mM 0.0290 mL 0.1448 mL 0.2895 mL 0.7239 mL
60 mM 0.0241 mL 0.1206 mL 0.2413 mL 0.6032 mL
80 mM 0.0181 mL 0.0905 mL 0.1810 mL 0.4524 mL
100 mM 0.0145 mL 0.0724 mL 0.1448 mL 0.3619 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Boc-Gln-Ala-Arg-AMC acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boc-Gln-Ala-Arg-AMCSer/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasesfluorogenic substratetrypsinTMPRSS2Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Boc-Gln-Ala-Arg-AMC acetate
Cat. No.:
HY-134432B
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.