2. PROTAC GPCR/G Protein MAPK/ERK Pathway
  3. Molecular Glues Ras
  4. BTX-7312

BTX-7312 is a cereblon-based SOS1 bifunctional degrader and a molecular glue. BTX-7312 reduces downstream signaling markers pERK and pS6 and shows antiproliferative activity in various KRAS-mutated cells.

For research use only. We do not sell to patients.

BTX-7312 Chemical Structure

BTX-7312 Chemical Structure

Size Price Stock Quantity
5 mg USD 780 Get quote 4 - 6 weeks 4 - 6 weeks 3 - 5 weeks
10 mg USD 1250 Get quote 4 - 6 weeks 4 - 6 weeks 3 - 5 weeks
25 mg USD 2550 Get quote 4 - 6 weeks 4 - 6 weeks 3 - 5 weeks
50 mg USD 4100 Get quote 4 - 6 weeks 4 - 6 weeks 3 - 5 weeks
100 mg   Get quote  
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Based on 1 publication(s) in Google Scholar

BTX-7312 Related Antibodies

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Description

BTX-7312 is a cereblon-based SOS1 bifunctional degrader and a molecular glue. BTX-7312 reduces downstream signaling markers pERK and pS6 and shows antiproliferative activity in various KRAS-mutated cells[1].

Molecular Weight

926.40

Formula

C45H52ClF4N9O6
SMILES

FC(F)(F)C1=CC([C@@H](C)NC2=NC(Cl)=NC3=C2CN(C(C4(OC)CCN(C(CCCCN5CCC(C6=CC(CN(C7CCC(NC7=O)=O)C8=O)=C8C=C6F)CC5)=O)CC4)=O)C3)=CC(N)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BTX-7312 Related Classifications

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BTX-7312BTX7312BTX 7312Molecular GluesRasCerebloncereblonpERKpS6KRASantiproliferativeInhibitorinhibitorinhibit

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