2. Neuronal Signaling
  3. Imidazoline Receptor
  4. BU226 hydrochloride

BU226 hydrochloride is a selective imidazoline 2 (I2) receptors ligand with an Ki of 1.4 nM for I2 and an IC50 of 534.5 nM for I1. BU226 hydrochloride can be used for researching antidepressant.

For research use only. We do not sell to patients.

BU226 hydrochloride Chemical Structure

BU226 hydrochloride Chemical Structure

CAS No. : 1186195-56-1

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5 mg USD 90 In-stock
10 mg USD 140 In-stock
25 mg USD 290 In-stock
50 mg USD 435 In-stock
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BU226 hydrochloride Related Antibodies

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Description

BU226 hydrochloride is a selective imidazoline 2 (I2) receptors ligand with an Ki of 1.4 nM for I2 and an IC50 of 534.5 nM for I1. BU226 hydrochloride can be used for researching antidepressant[1].

IC50 & Target

Ki: 1.4 nM (I2)[1]
IC50: 534.5 nM (I1)[1]
Molecular Weight

233.70

Formula

C12H12ClN3
CAS No.
Appearance

Solid

Color

White to light brown

SMILES

C1(C2=NCCN2)=CC3=C(C=N1)C=CC=C3.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (106.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2790 mL 21.3950 mL 42.7899 mL
5 mM 0.8558 mL 4.2790 mL 8.5580 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.2790 mL 21.3950 mL 42.7899 mL 106.9748 mL
5 mM 0.8558 mL 4.2790 mL 8.5580 mL 21.3950 mL
10 mM 0.4279 mL 2.1395 mL 4.2790 mL 10.6975 mL
15 mM 0.2853 mL 1.4263 mL 2.8527 mL 7.1317 mL
20 mM 0.2139 mL 1.0697 mL 2.1395 mL 5.3487 mL
25 mM 0.1712 mL 0.8558 mL 1.7116 mL 4.2790 mL
30 mM 0.1426 mL 0.7132 mL 1.4263 mL 3.5658 mL
40 mM 0.1070 mL 0.5349 mL 1.0697 mL 2.6744 mL
50 mM 0.0856 mL 0.4279 mL 0.8558 mL 2.1395 mL
60 mM 0.0713 mL 0.3566 mL 0.7132 mL 1.7829 mL
80 mM 0.0535 mL 0.2674 mL 0.5349 mL 1.3372 mL
100 mM 0.0428 mL 0.2139 mL 0.4279 mL 1.0697 mL
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BU226 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BU2261186195-56-1BU 226BU-226Imidazoline ReceptorantidepressantInhibitorinhibitorinhibit

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