Butylated hydroxytoluene-d₃

Name: Butylated hydroxytoluene-d 3
Brand: MedChemExpress
SKU: HY-Y0172S2
Rating: 4.5 (1 reviews)

Cat. No.: HY-Y0172S2 Purity: 99.21%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Butylated hydroxytoluene-d₃ is the deuterium labeled Butylated hydroxytoluene[1]. Butylated hydroxytoluene is an antioxidant widely used in foods and in food-related products[2]. Butylated hydroxytoluene is a Ferroptosis inhibitor[3].

For research use only. We do not sell to patients.

Butylated hydroxytoluene-d<sub>3</sub> Chemical Structure

Butylated hydroxytoluene-d₃ Chemical Structure

CAS No. : 86819-59-2

Size	Price	Stock	Quantity
5 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 95	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 185	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Butylated hydroxytoluene-d₃:

Butylated hydroxytoluene Get quote

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

223.37

Formula

C₁₅H₂₁D₃O

CAS No.

86819-59-2

Appearance

Solid

Color

White to yellow

SMILES

OC1=C(C(C)(C)C)C=C(C([2H])([2H])[2H])C=C1C(C)(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (447.69 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.4769 mL	22.3844 mL	44.7688 mL
5 mM	0.8954 mL	4.4769 mL	8.9538 mL
10 mM	0.4477 mL	2.2384 mL	4.4769 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.21%

Select Batch:

Data Sheet (275 KB) SDS (251 KB)

COA (253 KB) HNMR (207 KB) RP-HPLC (794 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Babich H, et al. Butylated hydroxytoluene (BHT): a review. Environ Res. 1982 Oct;29(1):1-29. [Content Brief]

[3]. Umemura T, et al. Butylhydroxytoluene (BHT) increases susceptibility of transgenic rasH2 mice to lung carcinogenesis. J Cancer Res Clin Oncol. 2001 Oct127(10):583-90. [Content Brief]

[4]. Stockwell BR, et al. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. ell. 2017 Oct 5171(2):273-285. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.4769 mL	22.3844 mL	44.7688 mL	111.9219 mL
	5 mM	0.8954 mL	4.4769 mL	8.9538 mL	22.3844 mL
	10 mM	0.4477 mL	2.2384 mL	4.4769 mL	11.1922 mL
	15 mM	0.2985 mL	1.4923 mL	2.9846 mL	7.4615 mL
	20 mM	0.2238 mL	1.1192 mL	2.2384 mL	5.5961 mL
	25 mM	0.1791 mL	0.8954 mL	1.7908 mL	4.4769 mL
	30 mM	0.1492 mL	0.7461 mL	1.4923 mL	3.7307 mL
	40 mM	0.1119 mL	0.5596 mL	1.1192 mL	2.7980 mL
	50 mM	0.0895 mL	0.4477 mL	0.8954 mL	2.2384 mL
	60 mM	0.0746 mL	0.3731 mL	0.7461 mL	1.8654 mL
	80 mM	0.0560 mL	0.2798 mL	0.5596 mL	1.3990 mL
	100 mM	0.0448 mL	0.2238 mL	0.4477 mL	1.1192 mL