2. Cytoskeleton
  3. Integrin
  4. c(avb6)-DOTA TFA

c(avb6)-DOTA TFA is a conjugate of the αvβ6 integrin selective peptide ring modified with DPTA chelator. The Lu(III) complex of c(avb6)-DOTA TFA has a comparable affinity for αvβ6 integrin (IC50=0.8 nM) and can be used as a tumor diagnostic.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

c(avb6)-DOTA TFA Chemical Structure

c(avb6)-DOTA TFA Chemical Structure

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1 mg USD 240 In-stock
5 mg USD 650 In-stock
10 mg USD 1040 In-stock
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Based on 1 publication(s) in Google Scholar

c(avb6)-DOTA TFA Related Antibodies

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View All Isoforms
αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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Description

c(avb6)-DOTA TFA is a conjugate of the αvβ6 integrin selective peptide ring modified with DPTA chelator. The Lu(III) complex of c(avb6)-DOTA TFA has a comparable affinity for αvβ6 integrin (IC50=0.8 nM) and can be used as a tumor diagnostic[1].

Molecular Weight

1546.65

Formula

C69H102F3N17O20
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (64.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6466 mL 3.2328 mL 6.4656 mL
5 mM 0.1293 mL 0.6466 mL 1.2931 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6466 mL 3.2328 mL 6.4656 mL 16.1640 mL
5 mM 0.1293 mL 0.6466 mL 1.2931 mL 3.2328 mL
10 mM 0.0647 mL 0.3233 mL 0.6466 mL 1.6164 mL
15 mM 0.0431 mL 0.2155 mL 0.4310 mL 1.0776 mL
20 mM 0.0323 mL 0.1616 mL 0.3233 mL 0.8082 mL
25 mM 0.0259 mL 0.1293 mL 0.2586 mL 0.6466 mL
30 mM 0.0216 mL 0.1078 mL 0.2155 mL 0.5388 mL
40 mM 0.0162 mL 0.0808 mL 0.1616 mL 0.4041 mL
50 mM 0.0129 mL 0.0647 mL 0.1293 mL 0.3233 mL
60 mM 0.0108 mL 0.0539 mL 0.1078 mL 0.2694 mL
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c(avb6)-DOTA TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

c(avb6)-DOTAIntegrinInhibitorinhibitorinhibit

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