C-di-IMP disodium (Synonyms: Cyclic-di-IMP disodium)

Cat. No.: HY-137724A Purity: 99.9%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

C-di-IMP disodium is a STING agonist. C-di-IMP disodium can be used in tumor research.

For research use only. We do not sell to patients.

C-di-IMP disodium Chemical Structure

Size	Price	Stock	Quantity
500 μg	USD 480	In-stock	Estimated Time of Arrival: December 31

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Other Forms of C-di-IMP disodium:

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Purity & Documentation
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Description

C-di-IMP disodium is a STING agonist. C-di-IMP disodium can be used in tumor research^[1].

Molecular Weight

704.35

Formula

C₂₀H₂₀N₈Na₂O₁₄P₂

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@](O[C@@](CO[P]2(O[Na])=O)([H])[C@@]1([H])O[P](OC[C@](O[C@](N3C(NC=NC4=O)=C4N=C3)([H])[C@@H]5O)([H])[C@@]5([H])O2)(O[Na])=O)([H])N6C(NC=NC7=O)=C7N=C6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (70.99 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.4197 mL	7.0987 mL	14.1975 mL
5 mM	0.2839 mL	1.4197 mL	2.8395 mL
10 mM	0.1420 mL	0.7099 mL	1.4197 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.9%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (255 KB)

Handling Instructions (2659 KB)

References

[1]. Tan. Xiangshi, et al. STING agonist and application of the IDO1 inhibitor drug combinations in antitumor. Patent. CN106552265A.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.4197 mL	7.0987 mL	14.1975 mL	35.4937 mL
	5 mM	0.2839 mL	1.4197 mL	2.8395 mL	7.0987 mL
	10 mM	0.1420 mL	0.7099 mL	1.4197 mL	3.5494 mL
	15 mM	0.0946 mL	0.4732 mL	0.9465 mL	2.3662 mL
	20 mM	0.0710 mL	0.3549 mL	0.7099 mL	1.7747 mL
	25 mM	0.0568 mL	0.2839 mL	0.5679 mL	1.4197 mL
	30 mM	0.0473 mL	0.2366 mL	0.4732 mL	1.1831 mL
	40 mM	0.0355 mL	0.1775 mL	0.3549 mL	0.8873 mL
	50 mM	0.0284 mL	0.1420 mL	0.2839 mL	0.7099 mL
	60 mM	0.0237 mL	0.1183 mL	0.2366 mL	0.5916 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

C-di-IMP disodium Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

C-di-IMP disodiumCyclic-di-IMP disodiumSTINGStimulator of Interferon GenesTMEM173MITAERISMPYSInhibitorinhibitorinhibit

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