2. Protein Tyrosine Kinase/RTK
  3. c-Met/HGFR
  4. c-Met-IN-15

c-Met-IN-15 (compound S3) is a c-Met kinase inhibitor. c-Met-IN-15 inhibits c-Met kinase activity of 21.1% at the concentration of 10 μM.

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c-Met-IN-15 Chemical Structure

c-Met-IN-15 Chemical Structure

CAS No. : 330572-32-2

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1 mg USD 75 In-stock
5 mg USD 190 In-stock
10 mg USD 285 In-stock
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Based on 1 publication(s) in Google Scholar

c-Met-IN-15 Related Antibodies

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Description

c-Met-IN-15 (compound S3) is a c-Met kinase inhibitor. c-Met-IN-15 inhibits c-Met kinase activity of 21.1% at the concentration of 10 μM[1].

Molecular Weight

299.26

Formula

C15H10FN3O3
CAS No.
Appearance

Solid

Color

Orange to reddish brown

SMILES

O=C(C1=CC=C(C=C1)O)N/N=C2C(NC3=CC=C(C=C\23)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (167.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3416 mL 16.7079 mL 33.4158 mL
5 mM 0.6683 mL 3.3416 mL 6.6832 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3416 mL 16.7079 mL 33.4158 mL 83.5394 mL
5 mM 0.6683 mL 3.3416 mL 6.6832 mL 16.7079 mL
10 mM 0.3342 mL 1.6708 mL 3.3416 mL 8.3539 mL
15 mM 0.2228 mL 1.1139 mL 2.2277 mL 5.5693 mL
20 mM 0.1671 mL 0.8354 mL 1.6708 mL 4.1770 mL
25 mM 0.1337 mL 0.6683 mL 1.3366 mL 3.3416 mL
30 mM 0.1114 mL 0.5569 mL 1.1139 mL 2.7846 mL
40 mM 0.0835 mL 0.4177 mL 0.8354 mL 2.0885 mL
50 mM 0.0668 mL 0.3342 mL 0.6683 mL 1.6708 mL
60 mM 0.0557 mL 0.2785 mL 0.5569 mL 1.3923 mL
80 mM 0.0418 mL 0.2088 mL 0.4177 mL 1.0442 mL
100 mM 0.0334 mL 0.1671 mL 0.3342 mL 0.8354 mL
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c-Met-IN-15 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

c-Met-IN-15330572-32-2c-Met/HGFRInhibitorinhibitorinhibit

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