C6 NBD Glucosylceramide

Cat. No.: HY-W356117 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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C6 NBD Glucosylceramide is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm). C6 NBD Glucosylceramide can be used to study the metabolism and internalization of glucosylceramide and also for the determination of glucosyl ceramide synthase activity.

For research use only. We do not sell to patients.

C6 NBD Glucosylceramide Chemical Structure

CAS No. : 94885-03-7

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100 μg	USD 300	In-stock	Estimated Time of Arrival: December 31
500 μg	USD 750	In-stock	Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

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Description	C6 NBD Glucosylceramide is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm). C6 NBD Glucosylceramide can be used to study the metabolism and internalization of glucosylceramide and also for the determination of glucosyl ceramide synthase activity^[1]^[2]^[3].
Molecular Weight	737.88
Formula	C₃₆H₅₉N₅O₁₁
CAS No.	94885-03-7
Appearance	Solid
Color	Yellow to orange
Emission (Em)	535
Excitation (Ex)	466
SMILES	OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCNC2=CC=C([N+]([O-])=O)C3=NON=C23)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation	Purity: ≥98.0% Select Batch: Data Sheet (264 KB) SDS (393 KB) COA (244 KB) Handling Instructions (2659 KB)
References	[1]. Kok JW, et al. Salvage of glucosylceramide by recycling after internalization along the pathway of receptor-mediated endocytosis. Proc Natl Acad Sci U S A. 1989 Dec;86(24):9896-900. [Content Brief] [2]. Hayashi Y, et al. A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates. Anal Biochem. 2005 Oct 15;345(2):181-6. [Content Brief] [3]. di Bartolomeo S, et al. Differential chemosensitizing effect of two glucosylceramide synthase inhibitors in hepatoma cells. Biochem Biophys Res Commun. 2001 Oct 19;288(1):269-74. [Content Brief]