1. Anti-infection
  2. HIV
  3. CA inhibitor 1

CA inhibitor 1  (Synonyms: GS-6207 analog)

Cat. No.: HY-124594 Purity: 99.94%
SDS COA Handling Instructions

CA inhibitor 1 (GS-6207 analog) is a potent HIV capsid inhibitor for HIV inhibition. CA inhibitor 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

CA inhibitor 1 Chemical Structure

CA inhibitor 1 Chemical Structure

CAS No. : 2189684-45-3

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 308 In-stock
Solution
10 mM * 1 mL in DMSO USD 308 In-stock
Solid
5 mg USD 280 In-stock
10 mg USD 450 In-stock
25 mg USD 940 In-stock
50 mg USD 1500 In-stock
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

CA inhibitor 1 (GS-6207 analog) is a potent HIV capsid inhibitor for HIV inhibition[1]. CA inhibitor 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

HIV[1]

Molecular Weight

958.34

Formula

C41H36ClF8N7O5S2

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(N[C@H](C1=NC(C#CC(S(=O)(C)=O)(C)C)=CC=C1C2=CC=C(Cl)C3=C2N(CC(F)F)N=C3NS(=O)(C4CC4)=O)CC5=CC(F)=CC(F)=C5)CN6N=C(C(F)F)C7=C6C(F)(F)[C@@]8([H])[C@]7([H])C8

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (52.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0435 mL 5.2174 mL 10.4347 mL
5 mM 0.2087 mL 1.0435 mL 2.0869 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.0435 mL 5.2174 mL 10.4347 mL 26.0868 mL
5 mM 0.2087 mL 1.0435 mL 2.0869 mL 5.2174 mL
10 mM 0.1043 mL 0.5217 mL 1.0435 mL 2.6087 mL
15 mM 0.0696 mL 0.3478 mL 0.6956 mL 1.7391 mL
20 mM 0.0522 mL 0.2609 mL 0.5217 mL 1.3043 mL
25 mM 0.0417 mL 0.2087 mL 0.4174 mL 1.0435 mL
30 mM 0.0348 mL 0.1739 mL 0.3478 mL 0.8696 mL
40 mM 0.0261 mL 0.1304 mL 0.2609 mL 0.6522 mL
50 mM 0.0209 mL 0.1043 mL 0.2087 mL 0.5217 mL
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CA inhibitor 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CA inhibitor 1
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