2. Cell Cycle/DNA Damage Cytoskeleton Autophagy
  3. Microtubule/Tubulin Autophagy
  4. Cabazitaxel-d6

Cabazitaxel-d6  (Synonyms: XRP6258-d6; RPR-116258A-d6; taxoid XRP6258-d6)

Cat. No.: HY-15459S Purity: 97.90%
SDS COA Handling Instructions

Molarity Calculator

Cabazitaxel-d6 is the deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity[1][2].

For research use only. We do not sell to patients.

Cabazitaxel-d<sub>6</sub> Chemical Structure

Cabazitaxel-d6 Chemical Structure

CAS No. : 1383561-29-2

Size Price Stock Quantity
500 μg USD 500 In-stock
1 mg USD 800 In-stock
5 mg   Get quote  
10 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Cabazitaxel-d6:

Cabazitaxel-d6 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Cabazitaxel-d6 is the deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cabazitaxel-d6 Related Antibodies
Molecular Weight

841.97

Formula

C45H51D6NO14
CAS No.
Unlabeled CAS

183133-96-2
Appearance

Solid

Color

White to off-white

SMILES

CC(O[C@]([C@@]1([H])C[C@@H]2OC([2H])([2H])[2H])(CO1)[C@@]([C@@]2(C([C@@H]3OC([2H])([2H])[2H])=O)C)([H])[C@@H]([C@@](C(C)(C3=C4C)C)(C[C@@H]4OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)O)OC(C6=CC=CC=C6)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (118.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 100 mg/mL (118.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1877 mL 5.9385 mL 11.8769 mL
5 mM 0.2375 mL 1.1877 mL 2.3754 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 97.90%

SDS (252 KB)

COA (265 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 1.1877 mL 5.9385 mL 11.8769 mL 29.6923 mL
5 mM 0.2375 mL 1.1877 mL 2.3754 mL 5.9385 mL
10 mM 0.1188 mL 0.5938 mL 1.1877 mL 2.9692 mL
15 mM 0.0792 mL 0.3959 mL 0.7918 mL 1.9795 mL
20 mM 0.0594 mL 0.2969 mL 0.5938 mL 1.4846 mL
25 mM 0.0475 mL 0.2375 mL 0.4751 mL 1.1877 mL
30 mM 0.0396 mL 0.1979 mL 0.3959 mL 0.9897 mL
40 mM 0.0297 mL 0.1485 mL 0.2969 mL 0.7423 mL
50 mM 0.0238 mL 0.1188 mL 0.2375 mL 0.5938 mL
60 mM 0.0198 mL 0.0990 mL 0.1979 mL 0.4949 mL
80 mM 0.0148 mL 0.0742 mL 0.1485 mL 0.3712 mL
100 mM 0.0119 mL 0.0594 mL 0.1188 mL 0.2969 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Cabazitaxel-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cabazitaxel-d61383561-29-2XRP6258-d6RPR-116258A-d6taxoid XRP6258-d6Microtubule/TubulinAutophagyInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Cabazitaxel-d6
Cat. No.:
HY-15459S
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (252 KB) Français - FR (252 KB) Deutsch - DE (252 KB) Norwegian - NO (252 KB) Español - ES (252 KB) Swedish - SV (252 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.