1. GPCR/G Protein Neuronal Signaling
  2. Cholecystokinin Receptor
  3. Caerulein acetate

Caerulein acetate is a decapeptide and a potent cholecystokinin receptor agonist. Ceruletide acetate is a safe and effective cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts.

For research use only. We do not sell to patients.

Caerulein acetate Chemical Structure

Caerulein acetate Chemical Structure

CAS No. : 2760881-68-1

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Top Publications Citing Use of Products

76 Publications Citing Use of MCE Caerulein acetate

RT-PCR
WB

    Caerulein acetate purchased from MedChemExpress. Usage Cited in: Exp Cell Res. 2019 Nov 1;384(1):111606.  [Abstract]

    Decreased SPOP expression in cerulein-induced CP mice. Pancreatic SPOP, NF-κB/p65 and downstream proteins are determined through western blotting. Protein levels are normalized to the GAPDH loading control. Densitometry analysis is performed using the ImageJ software.

    Caerulein acetate purchased from MedChemExpress. Usage Cited in: Can J Physiol Pharmacol. 2019 Jan;97(1):15-22.  [Abstract]

    Expressions of Wnt/β-Catenin pathway-related genes in pancreatic and small intestinal tissues in each group (control, Caerulein, SKL2001+Caerulein, SKL2001+control). Relative mRNA expressions of Wnt1 (A, F), Wnt2 (B, G), β-catenin (C, H), c-Myc (D, I) and Axin-2 (E, J) in pancreatic and small intestinal tissues in each group detected by qRT-PCR.

    Caerulein acetate purchased from MedChemExpress. Usage Cited in: Am J Transl Res. 2018 Feb 15;10(2):402-410.  [Abstract]

    Cerulein exposure increases the protein expression of MD2, while ALR reduces the Cerulein-induced upregulation in MD2 protein expression.

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    Description

    Caerulein acetate is a decapeptide and a potent cholecystokinin receptor agonist. Ceruletide acetate is a safe and effective cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts[1].

    Molecular Weight

    1412.46

    Formula

    C60H77N13O23S2

    CAS No.
    Sequence

    {Pyr}-Gln-Asp-{Tyr<SO3H>}-Thr-Gly-Trp-Met-Asp-Phe-NH2

    Sequence Shortening

    {Pyr}-QD-{Tyr<SO3H>}-TGWMDF-NH2

    SMILES

    CC(O)=O.NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC([C@H](CCSC)NC([C@@H](NC(CNC([C@H]([C@H](O)C)NC([C@@H](NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC([C@H]2NC(CC2)=O)=O)=O)=O)CC3=CC=C(C=C3)OS(=O)(O)=O)=O)=O)=O)CC4=CNC5=CC=CC=C45)=O)=O)=O)=O

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

    Purity & Documentation
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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
    Caerulein acetate
    Cat. No.:
    HY-158722
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