2. Membrane Transporter/Ion Channel
  3. Proton Pump
  4. Caloxin 2A1

Caloxin 2A1 is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg2+-ATPase or Na+-K+-ATPase.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Caloxin 2A1 Chemical Structure

Caloxin 2A1 Chemical Structure

CAS No. : 350670-85-8

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5 mg USD 110 In-stock
10 mg USD 180 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Caloxin 2A1:

Caloxin 2A1 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Caloxin 2A1

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Caloxin 2A1 is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg2+-ATPase or Na+-K+-ATPase[1].

In Vitro

Caloxin 2A1 inhibits Ca2+-Mg2+-ATPase in human erythrocyte leaky ghosts, but it does not affect basal Mg2+-ATPase or Na+-K+-ATPase in the ghosts or Ca2+-Mg2+-ATPase in the skeletal muscle sarcoplasmic reticulum. Caloxin 2A1 also inhibits Ca2+-dependent formation of the 140-kDa acid-stable acylphosphate[1].
Caloxin 2A1 increases airway smooth muscle cells (ASMCs) apoptosis[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Caloxin 2A1 Related Antibodies
Molecular Weight

1478.52

Formula

C64H91N19O22
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

VSNSNWPSFPSSGGG-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (67.64 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6764 mL 3.3818 mL 6.7635 mL
5 mM 0.1353 mL 0.6764 mL 1.3527 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6764 mL 3.3818 mL 6.7635 mL 16.9088 mL
5 mM 0.1353 mL 0.6764 mL 1.3527 mL 3.3818 mL
10 mM 0.0676 mL 0.3382 mL 0.6764 mL 1.6909 mL
15 mM 0.0451 mL 0.2255 mL 0.4509 mL 1.1273 mL
20 mM 0.0338 mL 0.1691 mL 0.3382 mL 0.8454 mL
25 mM 0.0271 mL 0.1353 mL 0.2705 mL 0.6764 mL
30 mM 0.0225 mL 0.1127 mL 0.2255 mL 0.5636 mL
40 mM 0.0169 mL 0.0845 mL 0.1691 mL 0.4227 mL
50 mM 0.0135 mL 0.0676 mL 0.1353 mL 0.3382 mL
60 mM 0.0113 mL 0.0564 mL 0.1127 mL 0.2818 mL
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Caloxin 2A1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Caloxin 2A1350670-85-8Proton PumpplasmamembraneCa2+peptideacylphosphateInhibitorinhibitorinhibit

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