1. Apoptosis
  2. Apoptosis
  3. Cardanol monoene

Cardanol monoene  (Synonyms: Cardanol C15:1)

Cat. No.: HY-119979 Purity: 98.02%
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Cardanol monoene (Cardanol C15:1) is a phenolic compound which can be found in cashew nut shell liquid. Cardanol monoene can induce mitochondria-associated apoptosis in human melanoma cells.

For research use only. We do not sell to patients.

Cardanol monoene Chemical Structure

Cardanol monoene Chemical Structure

CAS No. : 501-26-8

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1 mg USD 120 In-stock
5 mg USD 420 In-stock
10 mg USD 680 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Cardanol monoene (Cardanol C15:1) is a phenolic compound which can be found in cashew nut shell liquid. Cardanol monoene can induce mitochondria-associated apoptosis in human melanoma cells[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
9.09 μg/mL
Compound: 1, cardanol C15:1
Growth inhibition of human A549 cells after 2 days by SRB assay
Growth inhibition of human A549 cells after 2 days by SRB assay
[PMID: 9677265]
CCD-18Co IC50
54.58 μg/mL
Compound: 1, cardanol C15:1
Growth inhibition of human CCD-18Co cells after 2 days by SRB assay
Growth inhibition of human CCD-18Co cells after 2 days by SRB assay
[PMID: 9677265]
HCT-15 IC50
29.9 μg/mL
Compound: 1, cardanol C15:1
Growth inhibition of human HCT15 cells after 2 days by SRB assay
Growth inhibition of human HCT15 cells after 2 days by SRB assay
[PMID: 9677265]
HT1197 IC50
18.81 μg/mL
Compound: 1, cardanol C15:1
Growth inhibition of human HT1197 cells after 2 days by SRB assay
Growth inhibition of human HT1197 cells after 2 days by SRB assay
[PMID: 9677265]
MCF7 IC50
5.56 μg/mL
Compound: 1, cardanol C15:1
Growth inhibition of human MCF7 cells after 2 days by SRB assay
Growth inhibition of human MCF7 cells after 2 days by SRB assay
[PMID: 9677265]
SK-OV-3 IC50
12.9 μg/mL
Compound: 1, cardanol C15:1
Growth inhibition of human SKOV3 cells after 2 days by SRB assay
Growth inhibition of human SKOV3 cells after 2 days by SRB assay
[PMID: 9677265]
Molecular Weight

302.49

Formula

C21H34O

CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

OC1=CC=CC(CCCCCCC/C=C\CCCCCC)=C1

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 15 mg/mL (49.59 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3059 mL 16.5295 mL 33.0589 mL
5 mM 0.6612 mL 3.3059 mL 6.6118 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.02%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3059 mL 16.5295 mL 33.0589 mL 82.6474 mL
5 mM 0.6612 mL 3.3059 mL 6.6118 mL 16.5295 mL
10 mM 0.3306 mL 1.6529 mL 3.3059 mL 8.2647 mL
15 mM 0.2204 mL 1.1020 mL 2.2039 mL 5.5098 mL
20 mM 0.1653 mL 0.8265 mL 1.6529 mL 4.1324 mL
25 mM 0.1322 mL 0.6612 mL 1.3224 mL 3.3059 mL
30 mM 0.1102 mL 0.5510 mL 1.1020 mL 2.7549 mL
40 mM 0.0826 mL 0.4132 mL 0.8265 mL 2.0662 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cardanol monoene
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HY-119979
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