2. Cell Cycle/DNA Damage Anti-infection
  3. Topoisomerase DNA/RNA Synthesis Antibiotic Bacterial Orthopoxvirus
  4. 2408415-52-9

2408415-52-9

RyRs activator 2 Chemical Structure

2408415-52-9

Chemical Structure

  • RyRs activator 2
  • CAS No: 2408415-52-9
    Formula: C23H18Cl2F3N5O2
    Molecular Weight: 524.32
  • IUPAC Name: N-(4-chloro-2-(isopropylcarbamoyl)-6-methylphenyl)-1-(2-chloro-5-cyanophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
  • InChIKey: DXBACVIDBCHHCO-UHFFFAOYSA-N
  • SMILES: O=C(C1=CC(C(F)(F)F)=NN1C2=CC(C#N)=CC=C2Cl)NC3=C(C(NC(C)C)=O)C=C(Cl)C=C3C

Biological Activity: RyRs activator 2 (compound 7o) is a potent activator of ryanodine receptors (RyRs). RyRs activator 2 is 30% larvicidal activity, comparable to chlorantraniliprole (30%) and better than cyantraniliprole (10%)[1].

Cat. No. Product Name Purity Description
HY-146110 RyRs activator 2 RyRs activator 2 (compound 7o) is a potent activator of ryanodine receptors (RyRs). RyRs activator 2 is 30% larvicidal activity, comparable to chlorantraniliprole (30%) and better than cyantraniliprole (10%).

References

[1]. Liu J, et al. Discovery of a polysubstituted phenyl containing novel N-phenylpyrazole scaffold as potent ryanodine receptor activator. Bioorg Med Chem. 2020 Dec 15;28(24):115829. [Content Brief]

Keywords:

RyRs activator 2