2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 151038-96-9

151038-96-9

MC-DOXHZN Chemical Structure

151038-96-9

Chemical Structure

  • MC-DOXHZN
  • Synonym(s): (E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone
  • CAS No: 151038-96-9
    Formula: C37H42N4O13
    Molecular Weight: 750.75
  • IUPAC Name: N'-((Z)-1-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)-2-hydroxyethylidene)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanehydrazide
  • InChIKey: OBMJQRLIQQTJLR-LBMCFUDOSA-N
  • SMILES: [H][C@@]1(O[C@H]2C[C@@](/C(CO)=N\NC(CCCCCN3C(C=CC3=O)=O)=O)(O)CC(C2=C4O)=C(O)C5=C4C(C6=C(OC)C=CC=C6C5=O)=O)O[C@@H](C)[C@@H](O)[C@@H](N)C1

Biological Activity: MC-DOXHZN ((E/Z)-Aldoxorubicin) is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), with acid-sensitive properties[1].

Cat. No. Product Name Purity Description
HY-16261A MC-DOXHZN MC-DOXHZN ((E/Z)-Aldoxorubicin) is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), with acid-sensitive properties.

References

[1]. Sevim Rollas, et al. Hydrazone, Amide, Carbamate, Macromolecular and Other Prodrugs of Doxorubicin. The Open Drug Delivery Journal, 2008, 2, 77-85.

Keywords:

MC-DOXHZN