2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. 64748-79-4

64748-79-4

Azumolene Chemical Structure

64748-79-4

Chemical Structure

  • Azumolene
  • Synonym(s): EU4093 free base
  • CAS No: 64748-79-4
    Formula: C13H9BrN4O3
    Molecular Weight: 349.14
  • IUPAC Name: (E)-1-(((5-(4-bromophenyl)oxazol-2-yl)methylene)amino)imidazolidine-2,4-dione
  • InChIKey: SEGCNGONCZQFDW-OMCISZLKSA-N
  • SMILES: O=C1NC(CN1/N=C/C2=NC=C(C3=CC=C(Br)C=C3)O2)=O

Biological Activity: Azumolene (EU4093 free base), a Dantrolene analog, is a muscle relaxant. Azumolene is a ryanodine receptor (RyR) modulator and inhibits the calcium-release through ryanodine receptor. Azumolene can be used for malignant hyperthermia research[1][2].

Cat. No. Product Name Purity Description
HY-113920A Azumolene 99.11% Azumolene (EU4093 free base), a Dantrolene analog, is a muscle relaxant. Azumolene is a ryanodine receptor (RyR) modulator and inhibits the calcium-release through ryanodine receptor. Azumolene can be used for malignant hyperthermia research.

References

[1]. G C Leslie, et al. The effect of EU4093 (azumolene sodium) on the contraction of intrafusal muscle in the soleus muscle of the anaesthetized rat. Br J Pharmacol. 1989 Aug;97(4):1151-6. [Content Brief]
[2]. Viktor Yarotskyy, et al. Accelerated activation of SOCE current in myotubes from two mouse models of anesthetic- and heat-induced sudden death. PLoS One. 2013 Oct 15;8(10):e77633. [Content Brief]

Keywords:

Azumolene