Casein kinase 1δ-IN-7

Cat. No.: HY-156662 Purity: ≥95.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Casein kinase 1δ-IN-7 (compound 497) is a Casein kinase 1δ inhibitor. Casein kinase 1δ-IN-7 can be used in the study of neurodegenerative disorders such as Alzheimer's disease.

For research use only. We do not sell to patients.

Casein kinase 1δ-IN-7 Chemical Structure

CAS No. : 764694-25-9

Size	Stock	Quantity
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Based on 1 publication(s) in Google Scholar

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CK1 CK2

Biological Activity
Purity & Documentation
References
Customer Review

Description

Casein kinase 1δ-IN-7 (compound 497) is a Casein kinase 1δ inhibitor. Casein kinase 1δ-IN-7 can be used in the study of neurodegenerative disorders such as Alzheimer's disease^[1].

IC₅₀ & Target

Casein kinase 1δ^[1].

Molecular Weight

338.38

Formula

C₁₇H₁₄N₄O₂S

CAS No.

764694-25-9

Appearance

Solid

Color

White to light yellow

SMILES

N#CC1=CC=CC(NC(COC2=NC=NC3=C2C(C)=C(C)S3)=O)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (295.53 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.9553 mL	14.7763 mL	29.5526 mL
5 mM	0.5911 mL	2.9553 mL	5.9105 mL
10 mM	0.2955 mL	1.4776 mL	2.9553 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Purity & Documentation

Purity: ≥95.0%

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Data Sheet (273 KB) SDS (252 KB)

COA (255 KB) HNMR (208 KB)

Handling Instructions (2659 KB)

References

[1]. InventorJoseph M Sheridan, et al. CASEIN KINASE 1δ (CK1δ) INHIBITORS. Patent WO2012080729A2.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.9553 mL	14.7763 mL	29.5526 mL	73.8814 mL
	5 mM	0.5911 mL	2.9553 mL	5.9105 mL	14.7763 mL
	10 mM	0.2955 mL	1.4776 mL	2.9553 mL	7.3881 mL
	15 mM	0.1970 mL	0.9851 mL	1.9702 mL	4.9254 mL
	20 mM	0.1478 mL	0.7388 mL	1.4776 mL	3.6941 mL
	25 mM	0.1182 mL	0.5911 mL	1.1821 mL	2.9553 mL
	30 mM	0.0985 mL	0.4925 mL	0.9851 mL	2.4627 mL
	40 mM	0.0739 mL	0.3694 mL	0.7388 mL	1.8470 mL
	50 mM	0.0591 mL	0.2955 mL	0.5911 mL	1.4776 mL
	60 mM	0.0493 mL	0.2463 mL	0.4925 mL	1.2314 mL
	80 mM	0.0369 mL	0.1847 mL	0.3694 mL	0.9235 mL
	100 mM	0.0296 mL	0.1478 mL	0.2955 mL	0.7388 mL