2. Cell Cycle/DNA Damage PROTAC Autophagy
  3. CDK ATTECs
  4. CDK9 autophagic degrader 1

CDK9 autophagic degrader 1 (Compound 28) is a ATTEC degrader that can be used to degrade CDK9 and also affects the levels of the associated Cyclin T1. CDK9 autophagic degrader 1 shows over 80% CDK9 inhibition rate at 100 nM. ( Pink: LC3B ligand (HY-168897); Black: linker (HY-W017758); Blue: target protein ligand (HY-10008); linker + target protein ligand (HY-168898))

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CDK9 autophagic degrader 1 Chemical Structure

CDK9 autophagic degrader 1 Chemical Structure

CAS No. : 3066836-42-5

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Description

CDK9 autophagic degrader 1 (Compound 28) is a ATTEC degrader that can be used to degrade CDK9 and also affects the levels of the associated Cyclin T1. CDK9 autophagic degrader 1 shows over 80% CDK9 inhibition rate at 100 nM[1]. ( Pink: LC3B ligand (HY-168897); Black: linker (HY-W017758); Blue: target protein ligand (HY-10008); linker + target protein ligand (HY-168898))

IC50 & Target

CDK9

 

Molecular Weight

673.85

Formula

C34H39N7O4S2
CAS No.
SMILES

O=C(N1CC2=CC=CC=C2)N(CCCN3CCC(C(NC4=NC=C(SCC5=NC=C(C(C)(C)C)O5)S4)=O)CC3)C6=NC=CC=C6C1=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CDK9 autophagic degrader 1 Related Classifications

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Keywords:

CDK9 autophagic degrader 13066836-42-5CDKATTECsCyclin dependent kinaseAutophagosome-tethering compoundsInhibitorinhibitorinhibit

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