2. Anti-infection
  3. Bacterial Antibiotic
  4. Cefacetrile

Cefacetrile  (Synonyms: Cephacetrile; Cephacetril)

Cat. No.: HY-A0253 Purity: 98.38%
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Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection.

For research use only. We do not sell to patients.

Cefacetrile Chemical Structure

Cefacetrile Chemical Structure

CAS No. : 10206-21-0

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 110 In-stock
Solution
10 mM * 1 mL in DMSO USD 110 In-stock
Solid
5 mg USD 100 In-stock
10 mg USD 160 In-stock
25 mg USD 350 In-stock
50 mg USD 550 In-stock
100 mg USD 850 In-stock
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500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Cefacetrile:

Cefacetrile Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection[1][2].

IC50 & Target

β-lactam

 

In Vitro

Cefacetrile (less than 1 μg/mL) inhibits Staphylococcus aureusand Streptococcus pyogenes[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cefacetrile Related Antibodies
In Vivo

Cefacetrile (50, 100 and 500 mg/kg, s.c.) does not alter fertility, gestation and post-natal development of term foetuses of rats and fertility and gestation of rabbits[3].
Cefacetrile (1 g/kg, i.v.) produces no nephrotoxicity in rabbits and rats[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

339.32

Formula

C13H13N3O6S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C(N12)=C(COC(C)=O)CS[C@]2([H])[C@H](NC(CC#N)=O)C1=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (294.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9471 mL 14.7354 mL 29.4707 mL
5 mM 0.5894 mL 2.9471 mL 5.8941 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9471 mL 14.7354 mL 29.4707 mL 73.6768 mL
5 mM 0.5894 mL 2.9471 mL 5.8941 mL 14.7354 mL
10 mM 0.2947 mL 1.4735 mL 2.9471 mL 7.3677 mL
15 mM 0.1965 mL 0.9824 mL 1.9647 mL 4.9118 mL
20 mM 0.1474 mL 0.7368 mL 1.4735 mL 3.6838 mL
25 mM 0.1179 mL 0.5894 mL 1.1788 mL 2.9471 mL
30 mM 0.0982 mL 0.4912 mL 0.9824 mL 2.4559 mL
40 mM 0.0737 mL 0.3684 mL 0.7368 mL 1.8419 mL
50 mM 0.0589 mL 0.2947 mL 0.5894 mL 1.4735 mL
60 mM 0.0491 mL 0.2456 mL 0.4912 mL 1.2279 mL
80 mM 0.0368 mL 0.1842 mL 0.3684 mL 0.9210 mL
100 mM 0.0295 mL 0.1474 mL 0.2947 mL 0.7368 mL
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Cefacetrile Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cefacetrile10206-21-0Cephacetrile CephacetrilBacterialAntibioticinfectionfertilitygram-positivegram-negativeInhibitorinhibitorinhibit

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