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  4. CGP 53716

CGP 53716 is a potent protein tyrosine kinase inhibitor. CGP 53716 has selective activity of platelet-derived growth factor (PDGF) receptor. CGP 53716 can be used in the study of disease induced by abnormal cell proliferation induced by PDGF receptor activation .

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CGP 53716 Chemical Structure

CGP 53716 Chemical Structure

CAS No. : 152459-94-4

Size Price Stock Quantity
5 mg USD 180 In-stock
10 mg USD 290 In-stock
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Based on 1 publication(s) in Google Scholar

CGP 53716 Related Antibodies

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Description

CGP 53716 is a potent protein tyrosine kinase inhibitor. CGP 53716 has selective activity of platelet-derived growth factor (PDGF) receptor. CGP 53716 can be used in the study of disease induced by abnormal cell proliferation induced by PDGF receptor activation [1].

Molecular Weight

381.43

Formula

C23H19N5O
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(NC1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)C4=CC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (327.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6217 mL 13.1086 mL 26.2171 mL
5 mM 0.5243 mL 2.6217 mL 5.2434 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6217 mL 13.1086 mL 26.2171 mL 65.5428 mL
5 mM 0.5243 mL 2.6217 mL 5.2434 mL 13.1086 mL
10 mM 0.2622 mL 1.3109 mL 2.6217 mL 6.5543 mL
15 mM 0.1748 mL 0.8739 mL 1.7478 mL 4.3695 mL
20 mM 0.1311 mL 0.6554 mL 1.3109 mL 3.2771 mL
25 mM 0.1049 mL 0.5243 mL 1.0487 mL 2.6217 mL
30 mM 0.0874 mL 0.4370 mL 0.8739 mL 2.1848 mL
40 mM 0.0655 mL 0.3277 mL 0.6554 mL 1.6386 mL
50 mM 0.0524 mL 0.2622 mL 0.5243 mL 1.3109 mL
60 mM 0.0437 mL 0.2185 mL 0.4370 mL 1.0924 mL
80 mM 0.0328 mL 0.1639 mL 0.3277 mL 0.8193 mL
100 mM 0.0262 mL 0.1311 mL 0.2622 mL 0.6554 mL
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CGP 53716 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CGP 53716152459-94-4CGP53716CGP-53716Othersprotein-tyrosine kinase inhibitorplatelet-derived growth factorInhibitorinhibitorinhibit

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