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  3. Chalcone dibromide

Chalcone dibromide is a useful synthon in the synthesis of a large number of bioactive molecules such as pyrazolines, hydroxy pyrazolines, isoxazoles etc. Chalcone dibromide possesses antioxidant effects against tumor cells by inhibiting superoxide production and lipid peroxidation. Chalcone dibromide can be used for cancer disease research.

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Chalcone dibromide Chemical Structure

Chalcone dibromide Chemical Structure

CAS No. : 611-91-6

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Based on 1 publication(s) in Google Scholar

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Description

Chalcone dibromide is a useful synthon in the synthesis of a large number of bioactive molecules such as pyrazolines, hydroxy pyrazolines, isoxazoles etc. Chalcone dibromide possesses antioxidant effects against tumor cells by inhibiting superoxide production and lipid peroxidation. Chalcone dibromide can be used for cancer disease research[1].

Molecular Weight

368.06

Formula

C15H12Br2O

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=CC=C1)C(Br)C(Br)C2=CC=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (271.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7169 mL 13.5847 mL 27.1695 mL
5 mM 0.5434 mL 2.7169 mL 5.4339 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥95.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7169 mL 13.5847 mL 27.1695 mL 67.9237 mL
5 mM 0.5434 mL 2.7169 mL 5.4339 mL 13.5847 mL
10 mM 0.2717 mL 1.3585 mL 2.7169 mL 6.7924 mL
15 mM 0.1811 mL 0.9056 mL 1.8113 mL 4.5282 mL
20 mM 0.1358 mL 0.6792 mL 1.3585 mL 3.3962 mL
25 mM 0.1087 mL 0.5434 mL 1.0868 mL 2.7169 mL
30 mM 0.0906 mL 0.4528 mL 0.9056 mL 2.2641 mL
40 mM 0.0679 mL 0.3396 mL 0.6792 mL 1.6981 mL
50 mM 0.0543 mL 0.2717 mL 0.5434 mL 1.3585 mL
60 mM 0.0453 mL 0.2264 mL 0.4528 mL 1.1321 mL
80 mM 0.0340 mL 0.1698 mL 0.3396 mL 0.8490 mL
100 mM 0.0272 mL 0.1358 mL 0.2717 mL 0.6792 mL
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Chalcone dibromide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Chalcone dibromide
Cat. No.:
HY-W023983
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