1. Immunology/Inflammation
  2. Aryl Hydrocarbon Receptor
  3. CHD-5

CHD-5 is a potent AhR (aryl hydrocarbon receptor) antagonist.

For research use only. We do not sell to patients.

CHD-5 Chemical Structure

CHD-5 Chemical Structure

CAS No. : 289494-16-2

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1 mg USD 140 In-stock
5 mg USD 350 In-stock
10 mg USD 560 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

CHD-5 is a potent AhR (aryl hydrocarbon receptor) antagonist[1].

Molecular Weight

319.36

Formula

C19H17N3O2

CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=C(NC1=CC=C(C=C1C)/N=N/C2=CC=CC=C2C)C3=CC=CO3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (156.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1313 mL 15.6563 mL 31.3126 mL
5 mM 0.6263 mL 3.1313 mL 6.2625 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1313 mL 15.6563 mL 31.3126 mL 78.2816 mL
5 mM 0.6263 mL 3.1313 mL 6.2625 mL 15.6563 mL
10 mM 0.3131 mL 1.5656 mL 3.1313 mL 7.8282 mL
15 mM 0.2088 mL 1.0438 mL 2.0875 mL 5.2188 mL
20 mM 0.1566 mL 0.7828 mL 1.5656 mL 3.9141 mL
25 mM 0.1253 mL 0.6263 mL 1.2525 mL 3.1313 mL
30 mM 0.1044 mL 0.5219 mL 1.0438 mL 2.6094 mL
40 mM 0.0783 mL 0.3914 mL 0.7828 mL 1.9570 mL
50 mM 0.0626 mL 0.3131 mL 0.6263 mL 1.5656 mL
60 mM 0.0522 mL 0.2609 mL 0.5219 mL 1.3047 mL
80 mM 0.0391 mL 0.1957 mL 0.3914 mL 0.9785 mL
100 mM 0.0313 mL 0.1566 mL 0.3131 mL 0.7828 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CHD-5
Cat. No.:
HY-118780
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