2. Metabolic Enzyme/Protease
  3. Tyrosinase
  4. Chetoseminudin B

Chetoseminudin B possesses mushroom tyrosinase inhibitory activity with IC50 of 31.7 μM.

For research use only. We do not sell to patients.

Chetoseminudin B Chemical Structure

Chetoseminudin B Chemical Structure

CAS No. : 658711-87-6

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Chetoseminudin B Related Antibodies

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Description

Chetoseminudin B possesses mushroom tyrosinase inhibitory activity with IC50 of 31.7 μM[1].

IC50 & Target

IC50: 31.7 μM (mushroom tyrosinase)[1]
Cellular Effect
Cell Line Type Value Description References
HepG2 IC50
> 100 μM
Compound: 6
Cytotoxicity against human HepG2 cells by SRB method
Cytotoxicity against human HepG2 cells by SRB method
[PMID: 23079524]
Jurkat IC50
94.9 μM
Compound: 8
Cytotoxicity against human Jurkat cells after 40 hrs bioluminescence assay
Cytotoxicity against human Jurkat cells after 40 hrs bioluminescence assay
[PMID: 20303767]
MCF7 IC50
> 100 μM
Compound: 6
Cytotoxicity against human MCF7 cells by SRB method
Cytotoxicity against human MCF7 cells by SRB method
[PMID: 23079524]
NCI-H460 IC50
> 100 μM
Compound: 6
Cytotoxicity against human NCI-H460 cells by SRB method
Cytotoxicity against human NCI-H460 cells by SRB method
[PMID: 23079524]
SF-268 IC50
> 100 μM
Compound: 6
Cytotoxicity against human SF268 cells by SRB method
Cytotoxicity against human SF268 cells by SRB method
[PMID: 23079524]
T-cell IC50
24 μg/mL
Compound: 3, CS-C
Immunosuppressive activity in BALB/c mouse splenic T lymphocytes assessed as inhibition of Con A-induced cell proliferation after 72 hrs by MTT assay
Immunosuppressive activity in BALB/c mouse splenic T lymphocytes assessed as inhibition of Con A-induced cell proliferation after 72 hrs by MTT assay
[PMID: 14738397]
Molecular Weight

379.50

Formula

C17H21N3O3S2
CAS No.
SMILES

CS[C@]1(C(N([C@@](SC)(C(N1)=O)CO)C)=O)CC2=CNC3=CC=CC=C23
Structure Classification
Initial Source

Phaeosphaeria fuckelii
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Chetoseminudin B Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chetoseminudin B658711-87-6TyrosinaseMushroom tyrosinasePhaeosphaeria fuckeliiEndophytic fungusMelaninPeptidesInhibitorinhibitorinhibit

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HY-N10286
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