1. Metabolic Enzyme/Protease
  2. Amylases
  3. Chinese gallotannin

Chinese gallotannin is a non-specific promiscuous α-amylase inhibitor with a Ki of 0.82 μg/mL for human salivary α-amylase. Chinese gallotannin can be used for the research of diabetes.

For research use only. We do not sell to patients.

Chinese gallotannin Chemical Structure

Chinese gallotannin Chemical Structure

CAS No. : 5424-20-4

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100 mg USD 25 In-stock
500 mg USD 50 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Chinese gallotannin is a non-specific promiscuous α-amylase inhibitor with a Ki of 0.82 μg/mL for human salivary α-amylase. Chinese gallotannin can be used for the research of diabetes[1].

IC50 & Target

Ki: 0.82 μg/mL (Human Salivary α-Amylase)[1]
IC50: 2.3 μg/mL (Porcine Pancreatic α-Amylase), 128.9 nM (Telomerase), 3.0 μM (Fatty acid synthase), 6.9 μM (α-Ketoglutarate-Dependent Dioxygenase AlkB), 7.8 μM (5α-Reductase), 24.2 μM (Poly(ADP-ribose) Glycohydrolase)[1]

Molecular Weight

1701.20

Formula

C76H52O46

CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

O=C(C1=CC(OC(C2=CC(O)=C(C(O)=C2)O)=O)=C(C(O)=C1)O)O[C@@H]3[C@H]([C@@H](O[C@@H]([C@H]3OC(C4=CC(OC(C5=CC(O)=C(C(O)=C5)O)=O)=C(C(O)=C4)O)=O)COC(C6=CC(OC(C7=CC(O)=C(C(O)=C7)O)=O)=C(C(O)=C6)O)=O)OC(C8=CC(OC(C9=CC(O)=C(C(O)=C9)O)=O)=C(C(O)=C8)O)=O)OC(C%10=CC(OC(C%11=CC(O)=C(C(O)=C%11)O)=O)=C(C(O)=C%10)O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (58.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5878 mL 2.9391 mL 5.8782 mL
5 mM 0.1176 mL 0.5878 mL 1.1756 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥96.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.5878 mL 2.9391 mL 5.8782 mL 14.6955 mL
5 mM 0.1176 mL 0.5878 mL 1.1756 mL 2.9391 mL
10 mM 0.0588 mL 0.2939 mL 0.5878 mL 1.4696 mL
15 mM 0.0392 mL 0.1959 mL 0.3919 mL 0.9797 mL
20 mM 0.0294 mL 0.1470 mL 0.2939 mL 0.7348 mL
25 mM 0.0235 mL 0.1176 mL 0.2351 mL 0.5878 mL
30 mM 0.0196 mL 0.0980 mL 0.1959 mL 0.4899 mL
40 mM 0.0147 mL 0.0735 mL 0.1470 mL 0.3674 mL
50 mM 0.0118 mL 0.0588 mL 0.1176 mL 0.2939 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Chinese gallotannin
Cat. No.:
HY-135530
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