2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Cholestenone-13C

Cholestenone-13C  (Synonyms: 4-Cholesten-3-one-13C)

Cat. No.: HY-113365S1 Purity: ≥99.0%
SDS COA Handling Instructions

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Cholestenone-13C is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells[1][2][3].

For research use only. We do not sell to patients.

Cholestenone-<sup>13</sup>C Chemical Structure

Cholestenone-13C Chemical Structure

CAS No. : 68165-57-1

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1 mg USD 38 In-stock
5 mg USD 120 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Cholestenone-13C:

Cholestenone-13C Related Antibodies

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  • Purity & Documentation

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Description

Cholestenone-13C is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cholestenone-13C Related Antibodies
Molecular Weight

385.63

Formula

C2613CH44O
CAS No.
Unlabeled CAS

601-57-0
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(CC3)=[13CH]C(CC4)=O)C
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 50 mg/mL (129.66 mM; Need ultrasonic)

Ethanol : 50 mg/mL (129.66 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5932 mL 12.9658 mL 25.9316 mL
5 mM 0.5186 mL 2.5932 mL 5.1863 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

SDS (251 KB)

COA (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / Ethanol 1 mM 2.5932 mL 12.9658 mL 25.9316 mL 64.8290 mL
5 mM 0.5186 mL 2.5932 mL 5.1863 mL 12.9658 mL
10 mM 0.2593 mL 1.2966 mL 2.5932 mL 6.4829 mL
15 mM 0.1729 mL 0.8644 mL 1.7288 mL 4.3219 mL
20 mM 0.1297 mL 0.6483 mL 1.2966 mL 3.2414 mL
25 mM 0.1037 mL 0.5186 mL 1.0373 mL 2.5932 mL
30 mM 0.0864 mL 0.4322 mL 0.8644 mL 2.1610 mL
40 mM 0.0648 mL 0.3241 mL 0.6483 mL 1.6207 mL
50 mM 0.0519 mL 0.2593 mL 0.5186 mL 1.2966 mL
60 mM 0.0432 mL 0.2161 mL 0.4322 mL 1.0805 mL
80 mM 0.0324 mL 0.1621 mL 0.3241 mL 0.8104 mL
100 mM 0.0259 mL 0.1297 mL 0.2593 mL 0.6483 mL
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Cholestenone-13C Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cholestenone-13C68165-57-14-Cholesten-3-one-13CEndogenous MetaboliteInhibitorinhibitorinhibit

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