Cholesterol-¹³C₅

Cat. No.: HY-N0322S3 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Cholesterol-¹³C₅ is the ¹³C-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.

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Cholesterol-<sup>13</sup>C<sub>5</sub> Chemical Structure

Cholesterol-¹³C₅ Chemical Structure

CAS No. : 150044-24-9

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1 mg	USD 650	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

Other Forms of Cholesterol-¹³C₅:

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Description	Cholesterol-¹³C₅ is the ¹³C-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins^[1]^[2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist^[3].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Cholesterol-¹³C₅ Related Antibodies
Molecular Weight	391.62
Formula	C₂₂¹³C₅H₄₆O
CAS No.	150044-24-9
Unlabeled CAS	57-88-5
Appearance	Solid
Color	White to off-white
SMILES	C[C@@]12[C@](CC[C@]2([H])[C@H](C)C[13CH2][13CH2][13CH]([13CH3])[13CH3])([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation	Purity: ≥98.0% Select Batch: Data Sheet (268 KB) SDS (251 KB) COA (248 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief] [2]. Casaburi I, et al. Cholesterol as an Endogenous ERRα Agonist: A New Perspective to Cancer Treatment. Front Endocrinol (Lausanne). 2018 Sep 11;9:525. [Content Brief] [3]. Dietschy JM, et al. Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal. J Lipid Res. 2004 Aug;45(8):1375-97. [Content Brief] [4]. Fukui K, et al. Effect of Cholesterol Reduction on Receptor Signaling in Neurons. J Biol Chem. 2015 Sep 14. [Content Brief]