cis-Trismethoxy resveratrol (Synonyms: (Z)-3,5,4'-Trimethoxystilbene)

Cat. No.: HY-121989 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Cis-trismethoxy resveratrol is a potent anti-mitotic reagent.Cis-trismethoxy resveratrol inhibits tubulin polymerization with an IC₅₀ value of 4 μM.

For research use only. We do not sell to patients.

cis-Trismethoxy resveratrol Chemical Structure

CAS No. : 94608-23-8

Size	Stock	Quantity
Solvent
5 mg (184.97 mM * 100 μL in Ethanol)	In-stock	Estimated Time of Arrival: December 31
Solvent
10 mg (184.97 mM * 200 μL in Ethanol)	In-stock	Estimated Time of Arrival: December 31

Synthetic products have potential research and development risk.

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Cis-trismethoxy resveratrol is a potent anti-mitotic reagent.Cis-trismethoxy resveratrol inhibits tubulin polymerization with an IC₅₀ value of 4 μM^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
B16-F10	IC₅₀	1 μM Compound: 72	Anti cancer activity against mouse B16-F10 cells assessed as cell growth inhibition incubated for 40 hrs by Almar Blue stained fluorescence-based assay Anti cancer activity against mouse B16-F10 cells assessed as cell growth inhibition incubated for 40 hrs by Almar Blue stained fluorescence-based assay	[PMID: 32485531]
BXPC-3	GI₅₀	0.0034 μg/mL Compound: 1d	Growth inhibition of human BxPC3 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human BxPC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 19719153]
Caco-2	IC₅₀	0.08 μM Compound: 10	Cytotoxicity against human Caco-2 cells after 3 days by [3H]thymidine incorporation assay Cytotoxicity against human Caco-2 cells after 3 days by [3H]thymidine incorporation assay	[PMID: 20627379]
Caco-2	IC₅₀	0.145 μM Compound: 72	Anti cancer activity against human Caco-2 cell assessed as cell growth inhibition incubated for 48 hrs by Brdu assay Anti cancer activity against human Caco-2 cell assessed as cell growth inhibition incubated for 48 hrs by Brdu assay	[PMID: 32485531]
DU-145	GI₅₀	0.0054 μg/mL Compound: 1d	Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay	[PMID: 19719153]
HCT-116	IC₅₀	0.22 μM Compound: 8Z	Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay	[PMID: 21215623]
HepG2	IC₅₀	0.473 μM Compound: 72	Anti cancer activity against human HepG2 cell assessed as cell growth inhibition incubated for 48 hrs by Brdu assay Anti cancer activity against human HepG2 cell assessed as cell growth inhibition incubated for 48 hrs by Brdu assay	[PMID: 32485531]
HT-29	IC₅₀	0.04 μM Compound: 10	Cytotoxicity against human HT-29 cells after 3 days by [3H]thymidine incorporation assay Cytotoxicity against human HT-29 cells after 3 days by [3H]thymidine incorporation assay	[PMID: 20627379]
HT-29	IC₅₀	0.115 μM Compound: 72	Anti cancer activity against human HT-29 cell assessed as cell growth inhibition incubated for 48 hrs by Brdu assay Anti cancer activity against human HT-29 cell assessed as cell growth inhibition incubated for 48 hrs by Brdu assay	[PMID: 32485531]
HT-29	IC₅₀	54 nM Compound: 17	Antiproliferative activity against human HT29 cell line by methylene blue dye assay Antiproliferative activity against human HT29 cell line by methylene blue dye assay	[PMID: 17034147]
IMR-90	IC₅₀	0.23 μM Compound: 8Z	Cytotoxicity against human IMR90 cells after 24 hrs by MTT assay Cytotoxicity against human IMR90 cells after 24 hrs by MTT assay	[PMID: 21215623]
KB	IC₅₀	280 nM Compound: 17	Antiproliferative activity against human KB cell line by methylene blue dye assay Antiproliferative activity against human KB cell line by methylene blue dye assay	[PMID: 17034147]
MCF7	IC₅₀	0.12 μM Compound: 8Z	Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 21215623]
MKN-45	IC₅₀	218 nM Compound: 17	Antiproliferative activity against human MKN45 cell line by methylene blue dye assay Antiproliferative activity against human MKN45 cell line by methylene blue dye assay	[PMID: 17034147]
NCI-H460	GI₅₀	0.0028 μg/mL Compound: 1d	Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay	[PMID: 19719153]
NCI-H460	IC₅₀	253 nM Compound: 17	Antiproliferative activity against human H460 cell line by methylene blue dye assay Antiproliferative activity against human H460 cell line by methylene blue dye assay	[PMID: 17034147]
SF-268	GI₅₀	0.0044 μg/mL Compound: 1d	Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay	[PMID: 19719153]
SW480	IC₅₀	0.3 μM Compound: 4	Antiproliferative activity against human SW480 cells assessed as cell viability using propidium iodide staining after 48 hrs Antiproliferative activity against human SW480 cells assessed as cell viability using propidium iodide staining after 48 hrs	[PMID: 20395019]
SW480	IC₅₀	0.3 μM Compound: 4	Antiproliferative activity against human SW480 cells assessed as cell viability using propidium iodide staining after 72 hrs Antiproliferative activity against human SW480 cells assessed as cell viability using propidium iodide staining after 72 hrs	[PMID: 20395019]
TSGH 9201	IC₅₀	324 nM Compound: 17	Antiproliferative activity against human TSGH stomach carcinoma cell line by methylene blue dye assay Antiproliferative activity against human TSGH stomach carcinoma cell line by methylene blue dye assay	[PMID: 17034147]

Molecular Weight

270.32

Formula

C₁₇H₁₈O₃

CAS No.

94608-23-8

Appearance

Liquid

Color

Colorless to light yellow

SMILES

COC1=CC(/C=C\C2=CC=C(C=C2)OC)=CC(OC)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, protect from light, 2 years

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (253 KB)

Handling Instructions (2659 KB)

References

[1]. Schneider Y, et al. Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerization. Int J Cancer. 2003 Nov 1;107(2):189-96. [Content Brief]

cis-Trismethoxy resveratrol Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

cis-Trismethoxy resveratrol94608-23-8(Z)-3,5,4'-TrimethoxystilbeneMicrotubule/TubulinInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *

Organization Name *

Country or Region *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

cis-Trismethoxy resveratrol (Synonyms: (Z)-3,5,4'-Trimethoxystilbene)

cis-Trismethoxy resveratrol Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

cis-Trismethoxy resveratrol Related Classifications

Molarity Calculator

Dilution Calculator