2. Cell Cycle/DNA Damage Stem Cell/Wnt
  3. Casein Kinase
  4. CK2-IN-4

CK2-IN-4 (compound 5) is a protein kinase (CK2) inhibitor (IC50=8.6 µM). CK2-IN-4 has good potential for research in the areas of cancer, viral infections and glomerulonephritis.

For research use only. We do not sell to patients.

CK2-IN-4 Chemical Structure

CK2-IN-4 Chemical Structure

CAS No. : 313985-59-0

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Based on 1 publication(s) in Google Scholar

CK2-IN-4 Related Antibodies

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Description

CK2-IN-4 (compound 5) is a protein kinase (CK2) inhibitor (IC50=8.6 µM). CK2-IN-4 has good potential for research in the areas of cancer, viral infections and glomerulonephritis[1].

IC50 & Target

IC50: 8.6 µM (CK2)[1].
Molecular Weight

365.36

Formula

C18H11N3O4S
CAS No.
Appearance

Solid

Color

Orange to red

SMILES

O=C1C(C2=CSC(NC3=CC=CC=C3)=N2)=CC4=CC([N+]([O-])=O)=CC=C4O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (34.21 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7370 mL 13.6851 mL 27.3703 mL
5 mM 0.5474 mL 2.7370 mL 5.4741 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7370 mL 13.6851 mL 27.3703 mL 68.4257 mL
5 mM 0.5474 mL 2.7370 mL 5.4741 mL 13.6851 mL
10 mM 0.2737 mL 1.3685 mL 2.7370 mL 6.8426 mL
15 mM 0.1825 mL 0.9123 mL 1.8247 mL 4.5617 mL
20 mM 0.1369 mL 0.6843 mL 1.3685 mL 3.4213 mL
25 mM 0.1095 mL 0.5474 mL 1.0948 mL 2.7370 mL
30 mM 0.0912 mL 0.4562 mL 0.9123 mL 2.2809 mL
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CK2-IN-4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CK2-IN-4313985-59-0Casein Kinasecancerviral infectionsglomerulonephritisInhibitorinhibitorinhibit

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