2. Anti-infection
  3. Beta-lactamase Bacterial Antibiotic
  4. Clavulanate lithium

Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic.

For research use only. We do not sell to patients.

Clavulanate lithium Chemical Structure

Clavulanate lithium Chemical Structure

CAS No. : 61177-44-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 94 In-stock
Solution
10 mM * 1 mL in DMSO USD 94 In-stock
Solid
5 mg USD 85 In-stock
10 mg USD 140 In-stock
25 mg USD 280 In-stock
50 mg USD 450 In-stock
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Customer Review

Based on 5 publication(s) in Google Scholar

Other Forms of Clavulanate lithium:

Clavulanate lithium Related Antibodies

Top Publications Citing Use of Products

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Metallo-β-lactamase

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic[1][2].

IC50 & Target

β-lactam

 

In Vitro

Clavulanate lithium has weak antibacterial activity against most organisms when administered alone, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase[1].
Clavulanate lithium (0.25, 0.5 mg/L) causes a relatively slow inhibition of growth, and a higher concentration (1 mg/L) is only marginally more effective than 0.5 mg/L[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clavulanate lithium Related Antibodies

Cell Viability Assay[2]

Cell Line: L. pneumophila NCTC 1119
Concentration: 0.25 mg/L, 0.5 mg/L, 1 mg/L
Incubation Time: 0-35 hours
Result: Caused a relatively slow inhibition of growth.
Clinical Trial
Molecular Weight

205.09

Formula

C8H8LiNO5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@@H](/C(O[C@]1([H])C2)=C/CO)N1C2=O)O[Li]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 33.33 mg/mL (162.51 mM; Need ultrasonic)

DMSO : 4.17 mg/mL (20.33 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8759 mL 24.3795 mL 48.7591 mL
5 mM 0.9752 mL 4.8759 mL 9.7518 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.64%

COA (249 KB) HNMR (195 KB) LCMS (116 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 4.8759 mL 24.3795 mL 48.7591 mL 121.8977 mL
5 mM 0.9752 mL 4.8759 mL 9.7518 mL 24.3795 mL
10 mM 0.4876 mL 2.4380 mL 4.8759 mL 12.1898 mL
15 mM 0.3251 mL 1.6253 mL 3.2506 mL 8.1265 mL
20 mM 0.2438 mL 1.2190 mL 2.4380 mL 6.0949 mL
H2O 25 mM 0.1950 mL 0.9752 mL 1.9504 mL 4.8759 mL
30 mM 0.1625 mL 0.8127 mL 1.6253 mL 4.0633 mL
40 mM 0.1219 mL 0.6095 mL 1.2190 mL 3.0474 mL
50 mM 0.0975 mL 0.4876 mL 0.9752 mL 2.4380 mL
60 mM 0.0813 mL 0.4063 mL 0.8127 mL 2.0316 mL
80 mM 0.0609 mL 0.3047 mL 0.6095 mL 1.5237 mL
100 mM 0.0488 mL 0.2438 mL 0.4876 mL 1.2190 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Clavulanate lithium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Clavulanate61177-44-4Beta-lactamaseBacterialAntibioticβ-lactamaseAmoxycillinbeta-lactamasebeta-lactamInhibitorinhibitorinhibit

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