Clindamycin palmitate hydrochloride

Name: Clindamycin palmitate hydrochloride
Brand: MedChemExpress
SKU: HY-B1454
Rating: 4.5 (1 reviews)

Cat. No.: HY-B1454 Purity: 98.19%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Clindamycin palmitate hydrochloride is a hydrochloride salt of the ester of clindamycin and palmitic acid and it is an antibacterial agent. Clindamycin palmitate hydrochloride is inactive in vitro, rapid in vivo hydrolysis converts this compound to the antibacterially active clindamycin.

For research use only. We do not sell to patients.

Clindamycin palmitate hydrochloride Chemical Structure

CAS No. : 25507-04-4

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 55	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 55	In-stock	Estimated Time of Arrival: December 31
Solid
50 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Clindamycin palmitate hydrochloride:

Clindamycin hydrochloride In-stock
Clindamycin phosphate In-stock
Clindamycin palmitate hydrochloride (Standard) Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

699.85

Formula

C₃₄H₆₄Cl₂N₂O₆S

CAS No.

25507-04-4

Appearance

Solid

Color

White to off-white

SMILES

C[C@H](Cl)[C@@]([C@@]([C@@H]([C@H](O)[C@H]1OC(CCCCCCCCCCCCCCC)=O)O)([H])O[C@@H]1SC)([H])NC([C@@H]2C[C@@H](CCC)CN2C)=O.Cl[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (178.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 50 mg/mL (71.44 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.4289 mL	7.1444 mL	14.2888 mL
5 mM	0.2858 mL	1.4289 mL	2.8578 mL
10 mM	0.1429 mL	0.7144 mL	1.4289 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.08 mg/mL (2.97 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.19%

Select Batch:

Data Sheet (266 KB) SDS (252 KB)

COA (243 KB) HNMR (239 KB) LCMS (127 KB)

Handling Instructions (2659 KB)

References

[1]. Bharathi Ch, et al. Identification, isolation and characterization of impurities of clindamycin palmitate hydrochloride. J Pharm Biomed Anal. 2008 Dec 1;48(4):1211-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	1.4289 mL	7.1444 mL	14.2888 mL	35.7219 mL
	5 mM	0.2858 mL	1.4289 mL	2.8578 mL	7.1444 mL
	10 mM	0.1429 mL	0.7144 mL	1.4289 mL	3.5722 mL
	15 mM	0.0953 mL	0.4763 mL	0.9526 mL	2.3815 mL
	20 mM	0.0714 mL	0.3572 mL	0.7144 mL	1.7861 mL
	25 mM	0.0572 mL	0.2858 mL	0.5716 mL	1.4289 mL
	30 mM	0.0476 mL	0.2381 mL	0.4763 mL	1.1907 mL
	40 mM	0.0357 mL	0.1786 mL	0.3572 mL	0.8930 mL
	50 mM	0.0286 mL	0.1429 mL	0.2858 mL	0.7144 mL
	60 mM	0.0238 mL	0.1191 mL	0.2381 mL	0.5954 mL
DMSO	80 mM	0.0179 mL	0.0893 mL	0.1786 mL	0.4465 mL
DMSO	100 mM	0.0143 mL	0.0714 mL	0.1429 mL	0.3572 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.