2. GPCR/G Protein Neuronal Signaling
  3. Somatostatin Receptor
  4. Cortistatin 14 (mouse, rat)

Cortistatin 14 (mouse, rat)  (Synonyms: CST-14 (mouse, rat))

Cat. No.: HY-P1212 Purity: 99.96%
SDS COA Handling Instructions

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Cortistatin 14, mouse, rat (CST-14, human, rat), a neuropeptide with neuronal depressant and sleep modulating properties, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological activities and co-exists with GABA within the cortex and hippocampus.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Cortistatin 14 (mouse, rat) Chemical Structure

Cortistatin 14 (mouse, rat) Chemical Structure

CAS No. : 193829-96-8

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1 mg USD 150 In-stock
5 mg USD 380 In-stock
10 mg USD 600 In-stock
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Based on 1 publication(s) in Google Scholar

Cortistatin 14 (mouse, rat) Related Antibodies

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Description

Cortistatin 14, mouse, rat (CST-14, human, rat), a neuropeptide with neuronal depressant and sleep modulating properties, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological activities and co-exists with GABA within the cortex and hippocampus[1][2].

Molecular Weight

1721.01

Formula

C81H113N19O19S2
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys (Disulfide bridge: Cys2-Cys13)
Sequence Shortening

PCKNFFWKTFSSCK (Disulfide bridge: Cys2-Cys13)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (58.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5811 mL 2.9053 mL 5.8105 mL
5 mM 0.1162 mL 0.5811 mL 1.1621 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.96%

SDS (252 KB)

COA (264 KB) LCMS (96 KB) Elemental Analysis Report (124 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.5811 mL 2.9053 mL 5.8105 mL 14.5264 mL
5 mM 0.1162 mL 0.5811 mL 1.1621 mL 2.9053 mL
10 mM 0.0581 mL 0.2905 mL 0.5811 mL 1.4526 mL
15 mM 0.0387 mL 0.1937 mL 0.3874 mL 0.9684 mL
20 mM 0.0291 mL 0.1453 mL 0.2905 mL 0.7263 mL
25 mM 0.0232 mL 0.1162 mL 0.2324 mL 0.5811 mL
30 mM 0.0194 mL 0.0968 mL 0.1937 mL 0.4842 mL
40 mM 0.0145 mL 0.0726 mL 0.1453 mL 0.3632 mL
50 mM 0.0116 mL 0.0581 mL 0.1162 mL 0.2905 mL
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Cortistatin 14 (mouse, rat) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cortistatin 14 (mouse, rat)193829-96-8CST-14 (mouse, rat)Somatostatin ReceptorSSTRsSSTRInhibitorinhibitorinhibit

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