1. Immunology/Inflammation
  2. COX
  3. COX-1/2-IN-1

COX-1/2-IN-2 is a potent COX1/2 inhibitor. COX-1/2-IN-2 exhibits significant inhibitory effect against COX-1 and COX-2 inhibitor with IC50 values of 13.9 ± 3.21 µM and 6.4±0.74 µM, respectively.

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COX-1/2-IN-1 Chemical Structure

COX-1/2-IN-1 Chemical Structure

CAS No. : 2358849-47-3

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Description

COX-1/2-IN-2 is a potent COX1/2 inhibitor. COX-1/2-IN-2 exhibits significant inhibitory effect against COX-1 and COX-2 inhibitor with IC50 values of 13.9 ± 3.21 µM and 6.4±0.74 µM, respectively[1].

IC50 & Target[1]

COX-1

9.7±0.09 μM (IC50)

COX-2

4.6±1.45 μM (IC50)

Molecular Weight

349.61

Formula

C15H10BrClN2O

CAS No.
SMILES

CC1=[N+]([O-])C(C2=CC=C(Cl)C=C2)=NC3=CC=C(Br)C=C13

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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COX-1/2-IN-1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
COX-1/2-IN-1
Cat. No.:
HY-115966
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