2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. CRX000227

CRX000227 is a PPAR modulator. CRX000227 can be used for research of metabolic or cell proliferative disorders.

For research use only. We do not sell to patients.

CRX000227 Chemical Structure

CRX000227 Chemical Structure

CAS No. : 686769-92-6

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10 mg USD 75 In-stock
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Based on 1 publication(s) in Google Scholar

CRX000227 Related Antibodies

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View All PPAR Isoform Specific Products:

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PPARα PPARβ/δ PPARγ PPAR PPARδ

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Description

CRX000227 is a PPAR modulator. CRX000227 can be used for research of metabolic or cell proliferative disorders[1].

Molecular Weight

444.55

Formula

C25H24N4O2S
CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

O=C(N1CCN(CC1)C2=CC=C(C=C2)OC)C3=CN(C4=CC=CC=C4)N=C3C5=CC=CS5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (224.95 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2495 mL 11.2473 mL 22.4947 mL
5 mM 0.4499 mL 2.2495 mL 4.4989 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2495 mL 11.2473 mL 22.4947 mL 56.2366 mL
5 mM 0.4499 mL 2.2495 mL 4.4989 mL 11.2473 mL
10 mM 0.2249 mL 1.1247 mL 2.2495 mL 5.6237 mL
15 mM 0.1500 mL 0.7498 mL 1.4996 mL 3.7491 mL
20 mM 0.1125 mL 0.5624 mL 1.1247 mL 2.8118 mL
25 mM 0.0900 mL 0.4499 mL 0.8998 mL 2.2495 mL
30 mM 0.0750 mL 0.3749 mL 0.7498 mL 1.8746 mL
40 mM 0.0562 mL 0.2812 mL 0.5624 mL 1.4059 mL
50 mM 0.0450 mL 0.2249 mL 0.4499 mL 1.1247 mL
60 mM 0.0375 mL 0.1875 mL 0.3749 mL 0.9373 mL
80 mM 0.0281 mL 0.1406 mL 0.2812 mL 0.7030 mL
100 mM 0.0225 mL 0.1125 mL 0.2249 mL 0.5624 mL
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CRX000227 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CRX000227686769-92-6CRX 000227CRX-000227PPARPeroxisome proliferator-activated receptorsMetabolic diseaseproliferative disorderInhibitorinhibitorinhibit

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