2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. CXCR2 antagonist 4

CXCR2 antagonist 4 (compound 7) is a potent CXCR2 antagonist with an IC50 value of 0.13 μM. CXCR2 antagonist 4 can inhibit CXCL8-induced cytosolic calcium increase (IC50 = 27 μM). CXCR2 antagonist 4 can be used for researching anticancer.

For research use only. We do not sell to patients.

CXCR2 antagonist 4 Chemical Structure

CXCR2 antagonist 4 Chemical Structure

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CXCR2 antagonist 4 Related Antibodies

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Description

CXCR2 antagonist 4 (compound 7) is a potent CXCR2 antagonist with an IC50 value of 0.13 μM. CXCR2 antagonist 4 can inhibit CXCL8-induced cytosolic calcium increase (IC50 = 27 μM). CXCR2 antagonist 4 can be used for researching anticancer[1].

IC50 & Target[1]

CXCR2

0.13 μM (IC50)

Molecular Weight

368.42

Formula

C15H14F2N4OS2
SMILES

OC[C@@H](C)NC1=C2SC=NC2=NC(SCC3=CC=CC(F)=C3F)=N1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CXCR2 antagonist 4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CXCR2 antagonist 4CXCRCXC chemokine receptorsC-X-C motif chemokine receptorsAnticancerCytosolic calciumCXCL8Inhibitorinhibitorinhibit

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CXCR2 antagonist 4
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HY-144780
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