2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. CY 208-243

CY 208-243 is a selective dopamine D1 receptor agonist which exhibits antiparkinsonian activity.

For research use only. We do not sell to patients.

CY 208-243 Chemical Structure

CY 208-243 Chemical Structure

CAS No. : 100999-26-6

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 438 In-stock
Solution
10 mM * 1 mL in DMSO USD 438 In-stock
Solid
1 mg USD 145 In-stock
5 mg USD 285 In-stock
10 mg USD 485 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

CY 208-243 Related Antibodies

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  • Biological Activity

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  • References

  • Customer Review

Description

CY 208-243 is a selective dopamine D1 receptor agonist which exhibits antiparkinsonian activity[1].

IC50 & Target

D1 Receptor

 

In Vivo

Pretreatment with CY 208-243 (2.5 mg/kg; s.c.) prevents the increase of DA release and metabolism induced by the D-1 antagonist, SCH 23390 (0.05 mg/kg; s.c.)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats (180-200 g)[1]
Dosage: 2.5 mg/kg
Administration: Subcutaneous
Result: Prevented the increase of DA release and metabolism induced by the D-1 antagonist.
Molecular Weight

274.36

Formula

C19H18N2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN1[C@@](C2)([H])[C@@](C3=CC=CC=C3C1)([H])C4=CC=CC5=C4C2=CN5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (182.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6448 mL 18.2242 mL 36.4485 mL
5 mM 0.7290 mL 3.6448 mL 7.2897 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.98%

SDS (251 KB)

COA (250 KB) LCMS (260 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6448 mL 18.2242 mL 36.4485 mL 91.1212 mL
5 mM 0.7290 mL 3.6448 mL 7.2897 mL 18.2242 mL
10 mM 0.3645 mL 1.8224 mL 3.6448 mL 9.1121 mL
15 mM 0.2430 mL 1.2149 mL 2.4299 mL 6.0747 mL
20 mM 0.1822 mL 0.9112 mL 1.8224 mL 4.5561 mL
25 mM 0.1458 mL 0.7290 mL 1.4579 mL 3.6448 mL
30 mM 0.1215 mL 0.6075 mL 1.2149 mL 3.0374 mL
40 mM 0.0911 mL 0.4556 mL 0.9112 mL 2.2780 mL
50 mM 0.0729 mL 0.3645 mL 0.7290 mL 1.8224 mL
60 mM 0.0607 mL 0.3037 mL 0.6075 mL 1.5187 mL
80 mM 0.0456 mL 0.2278 mL 0.4556 mL 1.1390 mL
100 mM 0.0364 mL 0.1822 mL 0.3645 mL 0.9112 mL
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CY 208-243 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CY 208-243100999-26-6Dopamine ReceptorDopamineD1Inhibitorinhibitorinhibit

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