Cyclic AMP-¹³C₅ (Synonyms: Cyclic adenosine monophosphate-¹³C₅; Adenosine cyclic 3', 5'-monophosphate-¹³C₅; cAMP-¹³C₅)

Cat. No.: HY-B1511S: FAQs
Data Sheet SDS COA Handling Instructions

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Cyclic AMP-¹³C₅ is a deuterated cyclic AMP.

For research use only. We do not sell to patients.

Cyclic AMP-<sup>13</sup>C<sub>5</sub> Chemical Structure

Cyclic AMP-¹³C₅ Chemical Structure

CAS No. : 2170095-23-3

Size	Price	Stock	Quantity
500 μg	USD 1150	Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31

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Other Forms of Cyclic AMP-¹³C₅:

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Description

Cyclic AMP-¹³C₅ is a deuterated cyclic AMP.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

334.17

Formula

C₅¹³C₅H₁₂N₅O₆P

CAS No.

2170095-23-3

Unlabeled CAS

60-92-4

Appearance

Solid

Color

Off-white to light yellow

SMILES

NC1=C2N=CN([13C@@H]3O[13C@]4([H])[13CH2]OP(O)(O[13C@@]4([H])[13C@H]3O)=O)C2=NC=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

0.1 M NaOH : 30 mg/mL (89.77 mM; ultrasonic and warming and adjust pH to 6 with NaOH)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.9925 mL	14.9624 mL	29.9249 mL
5 mM	0.5985 mL	2.9925 mL	5.9850 mL
10 mM	0.2992 mL	1.4962 mL	2.9925 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 97.45%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (256 KB) Elemental Analysis Report (116 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-226. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

0.1 M NaOH	1 mM	2.9925 mL	14.9624 mL	29.9249 mL	74.8122 mL
	5 mM	0.5985 mL	2.9925 mL	5.9850 mL	14.9624 mL
	10 mM	0.2992 mL	1.4962 mL	2.9925 mL	7.4812 mL
	15 mM	0.1995 mL	0.9975 mL	1.9950 mL	4.9875 mL
	20 mM	0.1496 mL	0.7481 mL	1.4962 mL	3.7406 mL
	25 mM	0.1197 mL	0.5985 mL	1.1970 mL	2.9925 mL
	30 mM	0.0997 mL	0.4987 mL	0.9975 mL	2.4937 mL
	40 mM	0.0748 mL	0.3741 mL	0.7481 mL	1.8703 mL
	50 mM	0.0598 mL	0.2992 mL	0.5985 mL	1.4962 mL
	60 mM	0.0499 mL	0.2494 mL	0.4987 mL	1.2469 mL
	80 mM	0.0374 mL	0.1870 mL	0.3741 mL	0.9352 mL

Cyclic AMP-¹³C₅ Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclic AMP-¹³C₅2170095-23-3Cyclic adenosine monophosphate-¹³C₅ Adenosine cyclic 3', 5'-monophosphate-¹³C₅ cAMP-¹³C₅Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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Cyclic AMP-13C5 (Synonyms: Cyclic adenosine monophosphate-13C5; Adenosine cyclic 3', 5'-monophosphate-13C5; cAMP-13C5)

Other Forms of Cyclic AMP-13C5:

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Complete Stock Solution Preparation Table

Cyclic AMP-13C5 Related Classifications