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  3. Amino Acid Derivatives
  4. Cys-Penetratin

Cys-Penetratin is a cell-penetrating peptide (CPP) with sequence of CRQIKIWFQNRRMKWKK.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Cys-Penetratin Chemical Structure

Cys-Penetratin Chemical Structure

CAS No. : 209323-98-8

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1 mg USD 50 In-stock
5 mg USD 150 In-stock
10 mg USD 240 In-stock
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Based on 1 publication(s) in Google Scholar

Cys-Penetratin Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

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Description

Cys-Penetratin is a cell-penetrating peptide (CPP) with sequence of CRQIKIWFQNRRMKWKK[1].

Cellular Effect
Cell Line Type Value Description References
Caco-2 IC50
> 100 μM
Compound: 9a
Antiproliferative activity against human Caco2 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human Caco2 cells after 48 hrs by sulforhodamine B assay
[PMID: 28495087]
HT-29 IC50
> 100 μM
Compound: 9a
Antiproliferative activity against human HT-29 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HT-29 cells after 48 hrs by sulforhodamine B assay
[PMID: 28495087]
MKN-28 IC50
> 100 μM
Compound: 9a
Antiproliferative activity against human MKN28 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MKN28 cells after 48 hrs by sulforhodamine B assay
[PMID: 28495087]
Molecular Weight

2349.87

Formula

C107H173N35O21S2
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Cys-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys
Sequence Shortening

CRQIKIWFQNRRMKWKK
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (42.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4256 mL 2.1278 mL 4.2556 mL
5 mM 0.0851 mL 0.4256 mL 0.8511 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.4256 mL 2.1278 mL 4.2556 mL 10.6389 mL
5 mM 0.0851 mL 0.4256 mL 0.8511 mL 2.1278 mL
10 mM 0.0426 mL 0.2128 mL 0.4256 mL 1.0639 mL
15 mM 0.0284 mL 0.1419 mL 0.2837 mL 0.7093 mL
20 mM 0.0213 mL 0.1064 mL 0.2128 mL 0.5319 mL
25 mM 0.0170 mL 0.0851 mL 0.1702 mL 0.4256 mL
30 mM 0.0142 mL 0.0709 mL 0.1419 mL 0.3546 mL
40 mM 0.0106 mL 0.0532 mL 0.1064 mL 0.2660 mL
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Cys-Penetratin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cys-Penetratin209323-98-8Amino Acid DerivativesInhibitorinhibitorinhibit

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