2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. Cytembena

Cytembena is inhibitor for replicative DNA synthesis, purine synthesis and tetrahydrofolate formylase activity. Cytembena ameliorates ovarian or breast cancer, relieves the pain from skeletal metastases.

For research use only. We do not sell to patients.

Cytembena Chemical Structure

Cytembena Chemical Structure

CAS No. : 21739-91-3

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5 mg USD 285 In-stock
10 mg USD 460 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Cytembena is inhibitor for replicative DNA synthesis, purine synthesis and tetrahydrofolate formylase activity. Cytembena ameliorates ovarian or breast cancer, relieves the pain from skeletal metastases[1][2].

Molecular Weight

307.07

Formula

C11H8BrNaO4
CAS No.
Appearance

Solid

SMILES

O=C(O[Na])/C=C(Br)\C(C1=CC=C(C=C1)OC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (162.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2566 mL 16.2829 mL 32.5659 mL
5 mM 0.6513 mL 3.2566 mL 6.5132 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2566 mL 16.2829 mL 32.5659 mL 81.4147 mL
5 mM 0.6513 mL 3.2566 mL 6.5132 mL 16.2829 mL
10 mM 0.3257 mL 1.6283 mL 3.2566 mL 8.1415 mL
15 mM 0.2171 mL 1.0855 mL 2.1711 mL 5.4276 mL
20 mM 0.1628 mL 0.8141 mL 1.6283 mL 4.0707 mL
25 mM 0.1303 mL 0.6513 mL 1.3026 mL 3.2566 mL
30 mM 0.1086 mL 0.5428 mL 1.0855 mL 2.7138 mL
40 mM 0.0814 mL 0.4071 mL 0.8141 mL 2.0354 mL
50 mM 0.0651 mL 0.3257 mL 0.6513 mL 1.6283 mL
60 mM 0.0543 mL 0.2714 mL 0.5428 mL 1.3569 mL
80 mM 0.0407 mL 0.2035 mL 0.4071 mL 1.0177 mL
100 mM 0.0326 mL 0.1628 mL 0.3257 mL 0.8141 mL
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Cytembena Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cytembena21739-91-3DNA/RNA SynthesisICR miceWistar ratsCY-resistant tumorsanalgesicInhibitorinhibitorinhibit

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