2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. Nucleoside Antimetabolite/Analog Endogenous Metabolite
  4. Cytidine-d2

Cytidine-d2  (Synonyms: Cytosine β-D-riboside-d2; Cytosine-1-β-D-ribofuranoside-d2)

Cat. No.: HY-B0158S Purity: ≥98.0%
SDS COA Handling Instructions

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Cytidine-d2 is the deuterium labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[1][2][3].

For research use only. We do not sell to patients.

Cytidine-d<sub>2</sub> Chemical Structure

Cytidine-d2 Chemical Structure

CAS No. : 40632-25-5

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1 mg USD 190 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Cytidine-d2:

Cytidine-d2 Related Antibodies

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Description

Cytidine-d2 is the deuterium labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cytidine-d2 Related Antibodies
Molecular Weight

245.23

Formula

C9H11D2N3O5
CAS No.
Unlabeled CAS

65-46-3
Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)C([2H])=C2[2H])=O)O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (203.89 mM)

DMSO : 50 mg/mL (203.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 50 mg/mL (203.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 50 mg/mL (203.89 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0778 mL 20.3890 mL 40.7780 mL
5 mM 0.8156 mL 4.0778 mL 8.1556 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

SDS (252 KB)

COA (254 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO / DMSO / H2O 1 mM 4.0778 mL 20.3890 mL 40.7780 mL 101.9451 mL
5 mM 0.8156 mL 4.0778 mL 8.1556 mL 20.3890 mL
10 mM 0.4078 mL 2.0389 mL 4.0778 mL 10.1945 mL
15 mM 0.2719 mL 1.3593 mL 2.7185 mL 6.7963 mL
20 mM 0.2039 mL 1.0195 mL 2.0389 mL 5.0973 mL
25 mM 0.1631 mL 0.8156 mL 1.6311 mL 4.0778 mL
30 mM 0.1359 mL 0.6796 mL 1.3593 mL 3.3982 mL
40 mM 0.1019 mL 0.5097 mL 1.0195 mL 2.5486 mL
50 mM 0.0816 mL 0.4078 mL 0.8156 mL 2.0389 mL
60 mM 0.0680 mL 0.3398 mL 0.6796 mL 1.6991 mL
80 mM 0.0510 mL 0.2549 mL 0.5097 mL 1.2743 mL
100 mM 0.0408 mL 0.2039 mL 0.4078 mL 1.0195 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Cytidine-d2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cytidine-d240632-25-5Cytosine β-D-riboside-d2Cytosine-1-β-D-ribofuranoside-d2Nucleoside Antimetabolite/AnalogEndogenous MetaboliteInhibitorinhibitorinhibit

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