1. GPCR/G Protein
  2. GnRH Receptor
  3. (D-Trp6)-LHRH free acid

(D-Trp6)-LHRH free acid is a luteinizing hormone-releasing hormone (LHRH) agonist.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

(D-Trp6)-LHRH free acid Chemical Structure

(D-Trp6)-LHRH free acid Chemical Structure

CAS No. : 129418-54-8

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1 mg USD 60 In-stock
5 mg USD 140 In-stock
10 mg USD 225 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

(D-Trp6)-LHRH free acid is a luteinizing hormone-releasing hormone (LHRH) agonist[1].

In Vitro

(D-Trp6)-LHRH (10 μM; 24 h or 6 days) free acid reduces the proliferation of human epithelial ovarian cancer cell lines EFO-21 and EFO-27[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1312.43

Formula

C64H81N17O14

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{Pyr}-His-Trp-Ser-Tyr-{d-Trp}-Leu-Arg-Pro-Gly

Sequence Shortening

{Pyr}-HWSY-{d-Trp}-LRPG

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (76.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7619 mL 3.8097 mL 7.6195 mL
5 mM 0.1524 mL 0.7619 mL 1.5239 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7619 mL 3.8097 mL 7.6195 mL 19.0486 mL
5 mM 0.1524 mL 0.7619 mL 1.5239 mL 3.8097 mL
10 mM 0.0762 mL 0.3810 mL 0.7619 mL 1.9049 mL
15 mM 0.0508 mL 0.2540 mL 0.5080 mL 1.2699 mL
20 mM 0.0381 mL 0.1905 mL 0.3810 mL 0.9524 mL
25 mM 0.0305 mL 0.1524 mL 0.3048 mL 0.7619 mL
30 mM 0.0254 mL 0.1270 mL 0.2540 mL 0.6350 mL
40 mM 0.0190 mL 0.0952 mL 0.1905 mL 0.4762 mL
50 mM 0.0152 mL 0.0762 mL 0.1524 mL 0.3810 mL
60 mM 0.0127 mL 0.0635 mL 0.1270 mL 0.3175 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(D-Trp6)-LHRH free acid
Cat. No.:
HY-P4572
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