1. Immunology/Inflammation
  2. Kallikrein
  3. D-Val-Leu-Arg-pNA acetate

D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

D-Val-Leu-Arg-pNA acetate Chemical Structure

D-Val-Leu-Arg-pNA acetate Chemical Structure

CAS No. : 162303-66-4

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Based on 1 publication(s) in Google Scholar

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Description

D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein[1].

Molecular Weight

566.65

Formula

C25H42N8O7

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{d-Val}-Leu-Arg-{pNA}

Sequence Shortening

{d-Val}-LR-{pNA}

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (88.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7648 mL 8.8238 mL 17.6476 mL
5 mM 0.3530 mL 1.7648 mL 3.5295 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7648 mL 8.8238 mL 17.6476 mL 44.1189 mL
5 mM 0.3530 mL 1.7648 mL 3.5295 mL 8.8238 mL
10 mM 0.1765 mL 0.8824 mL 1.7648 mL 4.4119 mL
15 mM 0.1177 mL 0.5883 mL 1.1765 mL 2.9413 mL
20 mM 0.0882 mL 0.4412 mL 0.8824 mL 2.2059 mL
25 mM 0.0706 mL 0.3530 mL 0.7059 mL 1.7648 mL
30 mM 0.0588 mL 0.2941 mL 0.5883 mL 1.4706 mL
40 mM 0.0441 mL 0.2206 mL 0.4412 mL 1.1030 mL
50 mM 0.0353 mL 0.1765 mL 0.3530 mL 0.8824 mL
60 mM 0.0294 mL 0.1471 mL 0.2941 mL 0.7353 mL
80 mM 0.0221 mL 0.1103 mL 0.2206 mL 0.5515 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
D-Val-Leu-Arg-pNA acetate
Cat. No.:
HY-114150D
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