2. Natural Products
  3. Plants Terpenoids
  4. other families Triterpenes
  5. Boswellia freerana
  6. Dammarenediol II

Dammarenediol II (Compound 3) is a compound isolated from the resin of Boswellia freerana.

For research use only. We do not sell to patients.

Dammarenediol II Chemical Structure

Dammarenediol II Chemical Structure

CAS No. : 14351-29-2

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1 mg USD 240 In-stock
5 mg USD 590 In-stock
10 mg USD 940 In-stock
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Based on 1 publication(s) in Google Scholar

Dammarenediol II Related Antibodies

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Description

Dammarenediol II (Compound 3) is a compound isolated from the resin of Boswellia freerana[1].

Molecular Weight

444.73

Formula

C30H52O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]1(CC[C@@]2([H])C3(C)C)[C@@](CC[C@@]4([H])[C@]1(CC[C@]4([H])[C@@](C)(O)CC/C=C(C)\C)C)([H])[C@]2(CC[C@@H]3O)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (112.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2486 mL 11.2428 mL 22.4856 mL
5 mM 0.4497 mL 2.2486 mL 4.4971 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (5.62 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2486 mL 11.2428 mL 22.4856 mL 56.2139 mL
5 mM 0.4497 mL 2.2486 mL 4.4971 mL 11.2428 mL
10 mM 0.2249 mL 1.1243 mL 2.2486 mL 5.6214 mL
15 mM 0.1499 mL 0.7495 mL 1.4990 mL 3.7476 mL
20 mM 0.1124 mL 0.5621 mL 1.1243 mL 2.8107 mL
25 mM 0.0899 mL 0.4497 mL 0.8994 mL 2.2486 mL
30 mM 0.0750 mL 0.3748 mL 0.7495 mL 1.8738 mL
40 mM 0.0562 mL 0.2811 mL 0.5621 mL 1.4053 mL
50 mM 0.0450 mL 0.2249 mL 0.4497 mL 1.1243 mL
60 mM 0.0375 mL 0.1874 mL 0.3748 mL 0.9369 mL
80 mM 0.0281 mL 0.1405 mL 0.2811 mL 0.7027 mL
100 mM 0.0225 mL 0.1124 mL 0.2249 mL 0.5621 mL
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Dammarenediol II Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dammarenediol II14351-29-2OthersInhibitorinhibitorinhibit

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